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    CG7798 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36798, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7798provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034092
    Locus tag
    Dmel_CG7798
    See related
    AllianceGenome:FB:FBgn0034092
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7798
    Summary
    Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular space. Orthologous to human LYZ (lysozyme). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7798 in Genome Data Viewer
    Location:
    52F11-52F11; 2-78 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16222112..16222627, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12109617..12110132, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene mrj Neighboring gene transfer RNA:Glutamic acid-CTC 1-1 Neighboring gene transfer RNA:Glutamic acid-TTC 1-2 Neighboring gene antisense RNA:CR43898 Neighboring gene uncharacterized protein Neighboring gene Transferrin 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the c-type lysozyme gene family in Anopheles gambiae. Li B, et al. Gene, 2005 Nov 7. PMID 16137842
    2. Investigating the Evolution of Drosophila STING-Dependent Antiviral Innate Immunity by Multispecies Comparison of 2'3'-cGAMP Responses. Hédelin L, et al. Mol Biol Evol, 2024 Mar 1. PMID 38377349, Free PMC Article
    3. Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Waterhouse RM, et al. Science, 2007 Jun 22. PMID 17588928, Free PMC Article
    4. Activating transcription factor 3 regulates immune and metabolic homeostasis. Rynes J, et al. Mol Cell Biol, 2012 Oct. PMID 22851689, Free PMC Article
    5. The loss of histone H3 lysine 9 acetylation due to dSAGA-specific dAda2b mutation influences the expression of only a small subset of genes. Zsindely N, et al. Nucleic Acids Res, 2009 Nov. PMID 19740772, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables lysozyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lysozyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lysozyme activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7798-PA
    NP_611098.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      16222112..16222627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137254.2 → NP_611098.1  uncharacterized protein Dmel_CG7798 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611098.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAB8
      Related
      FBpp0086336
      Conserved Domains (1) summary
      cd00119
      Location:18 → 139
      LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZAB8 A1ZAB8

    Gene LinkOut

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