U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ir56b Ionotropic receptor 56b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37250, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ir56bprovided by FlyBase
    Official Full Name
    Ionotropic receptor 56bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034456
    Locus tag
    Dmel_CG15121
    See related
    AllianceGenome:FB:FBgn0034456
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    56b; CG15121; DmelIR56b; Dmel\CG15121; IR56b
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in labellar taste bristle; leg taste bristle chemosensory neurons; proboscis; and tarsal segment. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Ir56b in Genome Data Viewer
    Location:
    56D15-56D15; 2-89 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19508167..19509653)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15395672..15397158)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44472 Neighboring gene transfer RNA:Histidine-GTG 1-5 Neighboring gene Ionotropic receptor 56c Neighboring gene Ionotropic receptor 56d

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ir56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila. Dweck HKM, et al. Curr Biol, 2022 Apr 25. PMID 35294865, Free PMC Article
    2. Molecular basis of fatty acid taste in Drosophila. Ahn JE, et al. Elife, 2017 Dec 12. PMID 29231818, Free PMC Article
    3. Mechanisms of lactic acid gustatory attraction in Drosophila. Stanley M, et al. Curr Biol, 2021 Aug 23. PMID 34197729
    4. Calcium Taste Avoidance in Drosophila. Lee Y, et al. Neuron, 2018 Jan 3. PMID 29276056, Free PMC Article
    5. Candidate ionotropic taste receptors in the Drosophila larva. Stewart S, et al. Proc Natl Acad Sci U S A, 2015 Apr 7. PMID 25825777, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ionotropic receptor 56b
    Names
    CG15121-PB
    CG15121-PC
    Ir56b-PB
    Ir56b-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19508167..19509653
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001414062.1 → NP_001400982.1  ionotropic receptor 56b, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBM7

    2. NM_001414063.1 → NP_001401019.1  ionotropic receptor 56b, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E3CTQ7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBM7 A1ZBM7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools