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    CG11110 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37337, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11110provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034535
    Locus tag
    Dmel_CG11110
    See related
    AllianceGenome:FB:FBgn0034535
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11110; Imp
    Summary
    Predicted to enable endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to be located in membrane. Predicted to be part of mitochondrial inner membrane peptidase complex. Is expressed in adult head. Orthologous to human IMMP2L (inner mitochondrial membrane peptidase subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11110 in Genome Data Viewer
    Location:
    57A8-57A8; 2-91 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20641742..20642558)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16529247..16530063)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene rigor mortis Neighboring gene uncharacterized protein Neighboring gene maf-S Neighboring gene RNA polymerase III subunit K Neighboring gene Threonyl-carbamoyl synthesis 1 Neighboring gene DNA methyltransferase 1 associated protein 1 Neighboring gene Leucine-rich tendon-specific protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial processing peptidases. Gakh O, et al. Biochim Biophys Acta, 2002 Sep 2. PMID 12191769
    2. The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F. Bugga L, et al. Mol Cell Biol, 2009 Jun. PMID 19332563, Free PMC Article
    3. An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion. Zhang S, et al. Genes Dev, 2006 Jul 15. PMID 16815999, Free PMC Article
    4. Seizure suppression through manipulating splicing of a voltage-gated sodium channel. Lin WH, et al. Brain, 2015 Apr. PMID 25681415, Free PMC Article
    5. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein processing involved in protein targeting to mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein processing involved in protein targeting to mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal peptide processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial inner membrane peptidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial inner membrane peptidase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11110-PA
    serine-type peptidase
    NP_611501.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20641742..20642558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137657.3 → NP_611501.1  uncharacterized protein Dmel_CG11110 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611501.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QQ12
      Related
      FBpp0085545
      Conserved Domains (2) summary
      cd06530
      Location:27 → 136
      S26_SPase_I; The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are ...
      TIGR02227
      Location:27 → 142
      sigpep_I_bact; signal peptidase I, bacterial type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4QQ12 Q4QQ12

    Gene LinkOut

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