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    CG14717 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41412, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14717provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0265271
    Locus tag
    Dmel_CG14717
    See related
    AllianceGenome:FB:FBgn0265271
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-SAGE:Wang-126; Dmel\CG14717
    Summary
    Predicted to enable carboxylesterase activity. Predicted to be involved in cellular lipid metabolic process. Predicted to be active in mitochondrion. Orthologous to human ABHD11 (abhydrolase domain containing 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14717 in Genome Data Viewer
    Location:
    86E16-86E16; 3-51 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11696509..11698327)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7522231..7524049)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene 48 related 3 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46011

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of sex-biased genes in the Drosophila ananassae subgroup. Grath S, et al. BMC Evol Biol, 2009 Dec 16. PMID 20015359, Free PMC Article
    2. ONT-Based Alternative Assemblies Impact on the Annotations of Unique versus Repetitive Features in the Genome of a Romanian Strain of Drosophila melanogaster. Bologa AM, et al. Int J Mol Sci, 2022 Nov 28. PMID 36499217, Free PMC Article
    3. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article
    4. Age-dependent chromosomal distribution of male-biased genes in Drosophila. Zhang YE, et al. Genome Res, 2010 Nov. PMID 20798392, Free PMC Article
    5. A cautionary note for retrocopy identification: DNA-based duplication of intron-containing genes significantly contributes to the origination of single exon genes. Zhang YE, et al. Bioinformatics, 2011 Jul 1. PMID 21551137, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carboxylesterase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables carboxylic ester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14717-PA
    CG14717-PB
    anon-SAGE:Wang-126
    NP_001262481.1
    NP_650106.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11696509..11698327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275552.1 → NP_001262481.1  uncharacterized protein Dmel_CG14717, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262481.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0ANB0, A0ANB2, A0ANB3, A0ANB5, Q9VGJ4
      Conserved Domains (3) summary
      COG0596
      Location:28 → 299
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:47 → 165
      Abhydrolase_5; Alpha/beta hydrolase family
      cl21494
      Location:249 → 301
      Abhydrolase; alpha/beta hydrolases

    2. NM_141849.1 → NP_650106.1  uncharacterized protein Dmel_CG14717, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650106.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0ANB0, A0ANB2, A0ANB3, A0ANB5, Q9VGJ4
      Related
      FBpp0081901, FBtr0082425
      Conserved Domains (3) summary
      COG0596
      Location:28 → 299
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:47 → 165
      Abhydrolase_5; Alpha/beta hydrolase family
      cl21494
      Location:249 → 301
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGJ4 Q9VGJ4

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