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    CG31122 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42221, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31122provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051122
    Locus tag
    Dmel_CG31122
    See related
    AllianceGenome:FB:FBgn0051122
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14308; CG7687; Dmel\CG31122
    Summary
    Predicted to be active in mitochondrion. Is expressed in several structures, including CNS glial cell; central brain primordium; ganglia; larval nervous system; and ventral nerve cord primordium. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 53. Orthologous to human C2orf69 (chromosome 2 open reading frame 69). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31122 in Genome Data Viewer
    Location:
    91A6-91A6; 3-63 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18406064..18412874, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14231786..14238596, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene kokopelli Neighboring gene uncharacterized protein Neighboring gene fruitless Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Computational-aided identification of genes regulated by the Drosophila vnd. Kang DN, et al. J Neurogenet, 2009. PMID 19863267
    2. Application of the gene search system to screen for longevity genes in Drosophila. Seong KH, et al. Biogerontology, 2001. PMID 11708722
    3. Evolutionary Dynamics of Abundant Stop Codon Readthrough. Jungreis I, et al. Mol Biol Evol, 2016 Dec. PMID 27604222, Free PMC Article
    4. Negative genetic correlation between longevity and its hormetic extension by dietary restriction in Drosophila melanogaster. Gomez FH, et al. Biogerontology, 2020 Apr. PMID 31786681
    5. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Mummery-Widmer JL, et al. Nature, 2009 Apr 23. PMID 19363474, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31122-PB
    CG31122-PC
    CG31122-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18406064..18412874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275782.1 → NP_001262711.1  uncharacterized protein Dmel_CG31122, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262711.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGF5
      Conserved Domains (1) summary
      pfam10561
      Location:21 → 453
      UPF0565; uncharacterized protein family UPF0565

    2. NM_001369998.1 → NP_001356888.1  uncharacterized protein Dmel_CG31122, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE69
      Conserved Domains (1) summary
      pfam10561
      Location:21 → 452
      UPF0565; Uncharacterized protein family UPF0565

    3. NM_001170176.2 → NP_001163647.1  uncharacterized protein Dmel_CG31122, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163647.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQJ5
      Conserved Domains (1) summary
      pfam10561
      Location:21 → 452
      UPF0565; uncharacterized protein family UPF0565
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGF5 A0A0B4KGF5
    Q8MQJ5 Q8MQJ5
    Q9VE69 Q9VE69

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