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    CG4374 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42767, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4374provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039078
    Locus tag
    Dmel_CG4374
    See related
    AllianceGenome:FB:FBgn0039078
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4374
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4374 in Genome Data Viewer
    Location:
    94F1-94F4; 3-79 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23408684..23472278, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19234406..19298000, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 94d Neighboring gene Ionotropic receptor 94e Neighboring gene uncharacterized protein Neighboring gene small nuclear RNA 7SK b Neighboring gene long non-coding RNA:CR44324 Neighboring gene Ionotropic receptor 94f Neighboring gene Ionotropic receptor 94g

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Essential gene prediction in Drosophila melanogaster using machine learning approaches based on sequence and functional features. Aromolaran O, et al. Comput Struct Biotechnol J, 2020. PMID 32257045, Free PMC Article
    2. A screen identifying genes responsive to Dpp and Wg signaling in the Drosophila developing wing. Hadar N, et al. Gene, 2012 Feb 15. PMID 22192913
    3. Spatial expression of transcription factors in Drosophila embryonic organ development. Hammonds AS, et al. Genome Biol, 2013 Dec 20. PMID 24359758, Free PMC Article
    4. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860, Free PMC Article
    5. RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1. Jones CI, et al. Nucleic Acids Res, 2016 Jan 8. PMID 26656493, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4374-PB
    CG4374-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23408684..23472278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142889.3 → NP_651146.2  uncharacterized protein Dmel_CG4374, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651146.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCM2
      Conserved Domains (3) summary
      sd00019
      Location:651 → 671
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:649 → 671
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:663 → 688
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001275945.2 → NP_001262874.1  uncharacterized protein Dmel_CG4374, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262874.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCM2
      Conserved Domains (3) summary
      sd00019
      Location:651 → 671
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:649 → 671
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:663 → 688
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VCM2 Q9VCM2

    Gene LinkOut

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