Ets96B Ets96B [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Ets96Bprovided by FlyBase
Official Full Name: Ets96Bprovided by FlyBase
Primary source: FLYBASE:FBgn0039225
Locus tag: Dmel_CG6892
See related: AllianceGenome:FB:FBgn0039225
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6892; Dmel\CG6892; Ets; ets96B; ETS96B
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including positive regulation of circadian sleep/wake cycle, sleep; regulation of dopamine receptor signaling pathway; and startle response. Predicted to be active in nucleus. Is expressed in adult gnathal ganglion; adult mushroom body; dopaminergic PPM1 neuron; eye; and synaptic neuropil domain. Used to study bipolar disorder and obesity. Orthologous to several human genes including ETV4 (ETS variant transcription factor 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (24788054..24797955)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (20613776..20623677)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of circadian sleep/wake cycle, sleep	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of dopamine receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in response to starvation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in startle response	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain