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    lobo lost boys [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 4379864, updated on 9-Dec-2024

    Summary

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    Official Symbol
    loboprovided by FlyBase
    Official Full Name
    lost boysprovided by FlyBase
    Primary source
    FLYBASE:FBgn0083946
    Locus tag
    Dmel_CG34110
    See related
    AllianceGenome:FB:FBgn0083946
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13661; CG13662; CG34110; Dmel\CG34110
    Summary
    Involved in flagellated sperm motility and sperm storage. Located in motile cilium. Is expressed in chordotonal neurons and spermatogonium. Orthologous to human DRC7 (dynein regulatory complex subunit 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See lobo in Genome Data Viewer
    Location:
    96C2-96C4; 3-87 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25169565..25193776, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20995287..21019498, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46474 Neighboring gene distal antenna-related Neighboring gene distal antenna Neighboring gene uncharacterized protein Neighboring gene Cadherin 96Ca Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila sperm motility in the reproductive tract. Yang Y, et al. Biol Reprod, 2011 May. PMID 21293028, Free PMC Article
    2. A Dnmt2-like protein mediates DNA methylation in Drosophila. Kunert N, et al. Development, 2003 Nov. PMID 12944428
    3. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Yang Y, et al. Mol Biol Cell, 2011 Apr. PMID 21289096, Free PMC Article
    4. Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila. Emerald BS, et al. Development, 2003 Mar. PMID 12571108
    5. The pipsqueak-domain proteins Distal antenna and Distal antenna-related restrict Hunchback neuroblast expression and early-born neuronal identity. Kohwi M, et al. Development, 2011 May. PMID 21429984, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in flagellated sperm motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in flagellated sperm motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sperm storage IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in motile cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lost boys
    Names
    CG34110-PC
    lobo-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25169565..25193776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001043292.2 → NP_001036757.1  lost boys [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036757.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V516
      Conserved Domains (1) summary
      pfam01841
      Location:154 → 228
      Transglut_core; Transglutaminase-like superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V516.1 Q4V516

    Gene LinkOut

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