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    CG7985 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42178, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7985provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028499
    Locus tag
    Dmel_CG7985
    See related
    AllianceGenome:FB:FBgn0028499
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH04120; Dmel\CG7985
    Summary
    Predicted to enable beta-N-acetylhexosaminidase activity. Located in mitochondrion. Is expressed in adult brain cell body rind; adult head; adult optic lobe; lamina; and photoreceptor cell R7. Orthologous to human HEXD (hexosaminidase D). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7985 in Genome Data Viewer
    Location:
    90F7-90F7; 3-62 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18199857..18215001)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14025579..14040723)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Mediator complex subunit 17 Neighboring gene uncharacterized protein Neighboring gene Sequence-specific single-stranded DNA-binding protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Generation and characterization of inner photoreceptor-specific enhancer-trap lines using a novel piggyBac-Gal4 element in Drosophila. Terzioğlu Kara E, et al. Arch Insect Biochem Physiol, 2020 Jun. PMID 32285519
    2. Genotype Influences Day-to-Day Variability in Sleep in Drosophila melanogaster. Wu KJ, et al. Sleep, 2018 Feb 1. PMID 29228366, Free PMC Article
    3. The exon junction complex differentially marks spliced junctions. Saulière J, et al. Nat Struct Mol Biol, 2010 Oct. PMID 20818392
    4. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article
    5. Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos. Lye CM, et al. Development, 2014 Oct. PMID 25294944, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables beta-N-acetylhexosaminidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables hexosaminidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hexosaminidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7985-PA
    CG7985-PB
    NP_001262699.1
    NP_650689.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18199857..18215001
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275770.1 → NP_001262699.1  uncharacterized protein Dmel_CG7985, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262699.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4H4, Q9VEB8
      Conserved Domains (2) summary
      cd06565
      Location:191 → 517
      GH20_GcnA-like; Glycosyl hydrolase family 20 (GH20) catalytic domain of N-acetyl-beta-D-glucosaminidase (GcnA, also known as BhsA) and related proteins. GcnA is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine ...
      pfam05300
      Location:78 → 170
      DUF737; Protein of unknown function (DUF737)

    2. NM_142432.3 → NP_650689.1  uncharacterized protein Dmel_CG7985, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650689.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4H4, Q9VEB8
      Related
      FBpp0082981
      Conserved Domains (2) summary
      cd06565
      Location:191 → 517
      GH20_GcnA-like; Glycosyl hydrolase family 20 (GH20) catalytic domain of N-acetyl-beta-D-glucosaminidase (GcnA, also known as BhsA) and related proteins. GcnA is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine ...
      pfam05300
      Location:78 → 170
      DUF737; Protein of unknown function (DUF737)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VEB8 Q9VEB8

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