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    CG10631 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35262, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10631provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032817
    Locus tag
    Dmel_CG10631
    See related
    AllianceGenome:FB:FBgn0032817
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10631
    Summary
    Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; gastric caecum; posterior endoderm; and spermatozoon. Orthologous to human ZNF212 (zinc finger protein 212) and ZNF671 (zinc finger protein 671). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10631 in Genome Data Viewer
    Location:
    38A2-38A2; 2-54 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19742817..19756904, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19742817..19756904, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Nuclear factor Y-box B Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Dihydrouridine synthase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic analysis provides insight into the mechanism of IKKβ-mediated suppression of HPV18E6-induced cellular abnormalities. Collins QP, et al. G3 (Bethesda), 2023 Apr 11. PMID 36722216, Free PMC Article
    2. Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila. Bushati N, et al. Curr Biol, 2008 Apr 8. PMID 18394895
    3. Neurological proteins are not enriched for repetitive sequences. Huntley MA, et al. Genetics, 2004 Mar. PMID 15082536, Free PMC Article
    4. A genetic screen and transcript profiling reveal a shared regulatory program for Drosophila linker histone H1 and chromatin remodeler CHD1. Kavi H, et al. G3 (Bethesda), 2015 Jan 27. PMID 25628309, Free PMC Article
    5. Analysis of Ras-induced overproliferation in Drosophila hemocytes. Asha H, et al. Genetics, 2003 Jan. PMID 12586708, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription corepressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10631-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19742817..19756904 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136154.2 → NP_609998.1  uncharacterized protein Dmel_CG10631 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609998.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIS5
      Related
      FBpp0080856
      Conserved Domains (4) summary
      smart00692
      Location:3396 → 3452
      DM3; Zinc finger domain in CG10631, C. elegans LIN-15B and human P52rIPK
      smart00980
      Location:1424 → 1493
      THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
      sd00017
      Location:288 → 311
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam05485
      Location:3621 → 3669
      THAP; THAP domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIS5 Q9VIS5

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