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    CG14722 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41419, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14722provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037943
    Locus tag
    Dmel_CG14722
    See related
    AllianceGenome:FB:FBgn0037943
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14722
    Summary
    Involved in defense response to Gram-negative bacterium. Is expressed in several structures, including antennal primordium; anterior endoderm; central brain primordium; embryonic/larval midgut primordium; and head epidermis primordium. Orthologous to human WDR55 (WD repeat domain 55). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14722 in Genome Data Viewer
    Location:
    86E17-86E17; 3-51 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11741890..11744027)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7567612..7569749)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Bloom syndrome helicase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic analysis of Drosophila melanogaster susceptibility to intestinal Vibrio cholerae infection. Berkey CD, et al. Cell Microbiol, 2009 Mar. PMID 19046341, Free PMC Article
    2. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article
    3. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14722-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11741890..11744027
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141854.4 → NP_650111.3  uncharacterized protein Dmel_CG14722 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650111.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8T088, Q9VGI7
      Related
      FBpp0081907
      Conserved Domains (3) summary
      COG2319
      Location:156 → 459
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:160 → 198
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:156 → 438
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T088.1 Q8T088

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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