Fhip1b FHF complex subunit HOOK interacting protein 1B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fhip1bprovided by RGD
Official Full Name: FHF complex subunit HOOK interacting protein 1Bprovided by RGD
Primary source: RGD:1359585
See related: EnsemblRapid:ENSRNOG00000017408 AllianceGenome:RGD:1359585
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: FHIP; Fam160a2
Summary: Predicted to be involved in several processes, including early endosome to late endosome transport; endosome to lysosome transport; and protein localization to perinuclear region of cytoplasm. Predicted to be part of FHF complex. Orthologous to human FHIP1B (FHF complex subunit HOOK interacting protein 1B). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 82.5), Kidney (RPKM 79.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q32

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (169137866..169160305, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (159718679..159748449, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (170216505..170238898, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in early endosome to late endosome transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in early endosome to late endosome transport	IEA Inferred from Electronic Annotation more info
involved_in early endosome to late endosome transport	ISO Inferred from Sequence Orthology more info
involved_in early endosome to late endosome transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in endosome organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in endosome organization	IEA Inferred from Electronic Annotation more info
involved_in endosome organization	ISO Inferred from Sequence Orthology more info
involved_in endosome organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in endosome to lysosome transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in endosome to lysosome transport	IEA Inferred from Electronic Annotation more info
involved_in endosome to lysosome transport	ISO Inferred from Sequence Orthology more info
involved_in endosome to lysosome transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in lysosome organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in lysosome organization	IEA Inferred from Electronic Annotation more info
involved_in lysosome organization	ISO Inferred from Sequence Orthology more info
involved_in lysosome organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein localization to perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info
involved_in protein localization to perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info
involved_in protein localization to perinuclear region of cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of FHF complex	IBA Inferred from Biological aspect of Ancestor more info
part_of FHF complex	IEA Inferred from Electronic Annotation more info
part_of FHF complex	ISO Inferred from Sequence Orthology more info
part_of FHF complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: FHF complex subunit HOOK-interacting protein 1B

Names: FTS and Hook-interacting protein; family with sequence similarity 160, member A2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005538.2 → NP_001005538.2 FHF complex subunit HOOK-interacting protein 1B

See identical proteins and their annotated locations for NP_001005538.2

Status: VALIDATED

Source sequence(s)

BC082011, BP493980, CA339001, CV112456

UniProtKB/TrEMBL

A0A8I5ZMH3, A0A8L2UJU3, A6I7H8

Related

ENSRNOP00000023502.7, ENSRNOT00000023502.8

Conserved Domains (1) summary

pfam10257
Location:97 → 426

RAI16-like; Retinoic acid induced 16-like protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

169137866..169160305 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006229932.5 → XP_006229994.1 FHF complex subunit HOOK-interacting protein 1B isoform X3

See identical proteins and their annotated locations for XP_006229994.1

UniProtKB/Swiss-Prot

Q66H54

UniProtKB/TrEMBL

A0A8I5ZMH3

Conserved Domains (1) summary

pfam10257
Location:97 → 426

RAI16-like; Retinoic acid induced 16-like protein
XM_063285569.1 → XP_063141639.1 FHF complex subunit HOOK-interacting protein 1B isoform X4
XM_006229931.5 → XP_006229993.1 FHF complex subunit HOOK-interacting protein 1B isoform X1

UniProtKB/TrEMBL

A0A8I5ZMH3

Related

ENSRNOP00000078432.1, ENSRNOT00000106363.2

Conserved Domains (1) summary

pfam10257
Location:97 → 426

RAI16-like; Retinoic acid induced 16-like protein
XM_063285567.1 → XP_063141637.1 FHF complex subunit HOOK-interacting protein 1B isoform X1
XM_063285572.1 → XP_063141642.1 FHF complex subunit HOOK-interacting protein 1B isoform X5
XM_008759708.4 → XP_008757930.1 FHF complex subunit HOOK-interacting protein 1B isoform X2

UniProtKB/TrEMBL

A0A8I5ZMH3

Conserved Domains (1) summary

pfam10257
Location:97 → 426

RAI16-like; Retinoic acid induced 16-like protein