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    Strip2 striatin interacting protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500066, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Strip2provided by RGD
    Official Full Name
    striatin interacting protein 2provided by RGD
    Primary source
    RGD:1588437
    See related
    EnsemblRapid:ENSRNOG00000057729 AllianceGenome:RGD:1588437
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cell migration; cytoskeleton organization; and regulation of cell shape. Predicted to be located in cytosol. Predicted to be part of FAR/SIN/STRIPAK complex. Orthologous to human STRIP2 (striatin interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 133.0), Heart (RPKM 69.1) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Strip2 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (59503478..59545745)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (58536034..58578279)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (57204850..57248912)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120102483 Neighboring gene adenosylhomocysteinase-like 2 Neighboring gene large ribosomal subunit protein eL19-like Neighboring gene phosphoglycerate kinase 1, pseudogene 1 Neighboring gene small lysine-rich protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. Bai SW, et al. BMC Biol, 2011 Aug 11. PMID 21834987, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of cell shape ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of FAR/SIN/STRIPAK complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    striatin-interacting protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427848.1 → NP_001414777.1  striatin-interacting protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A8I5ZP29, A0A8I6G7M4
      Related
      ENSRNOP00000081181.1, ENSRNOT00000112378.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      59503478..59545745
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286497.1 → XP_063142567.1  striatin-interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZP29, A0A8I6G7M4

    2. XM_063286498.1 → XP_063142568.1  striatin-interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZP29, A0A8I6G7M4

    3. XM_063286499.1 → XP_063142569.1  striatin-interacting protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZP29

    4. XM_063286500.1 → XP_063142570.1  striatin-interacting protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZP29
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.