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    Slc7a14 solute carrier family 7, member 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499587, updated on 9-Dec-2024

    Summary

    Symbol
    Slc7a14provided by RGD
    Full Name
    solute carrier family 7, member 14provided by RGD
    Primary source
    RGD:1594375
    See related
    AllianceGenome:RGD:1594375
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable gamma-aminobutyric acid transmembrane transporter activity. Predicted to be involved in gamma-aminobutyric acid import. Predicted to be located in cytosol; lysosomal membrane; and nucleoplasm. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 68. Orthologous to human SLC7A14 (solute carrier family 7 member 14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 91.2) See more
    Orthologs
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    Genomic context

    See Slc7a14 in Genome Data Viewer
    Location:
    2q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (113993781..114099810)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (112065286..112171319)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (115678344..115788688)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485729 Neighboring gene uncharacterized LOC134485893 Neighboring gene uncharacterized LOC134485894 Neighboring gene U1 spliceosomal RNA Neighboring gene claudin 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables gamma-aminobutyric acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in carboxylic acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in gamma-aminobutyric acid import ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 7 member 14
    Names
    probable cationic amino acid transporter
    solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
    solute carrier family 7 (orphan transporter), member 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134615.1NP_001128087.1  solute carrier family 7 member 14

      See identical proteins and their annotated locations for NP_001128087.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473961
      UniProtKB/TrEMBL
      A0A0G2K1G8, A6IHJ8
      Conserved Domains (1) summary
      pfam13906
      Location:268318
      AA_permease_C; C-terminus of AA_permease

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      113993781..114099810
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)