U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zdhhc20 zinc finger DHHC-type palmitoyltransferase 20 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305923, updated on 3-Dec-2024

    Summary

    Official Symbol
    Zdhhc20provided by RGD
    Official Full Name
    zinc finger DHHC-type palmitoyltransferase 20provided by RGD
    Primary source
    RGD:1305755
    See related
    EnsemblRapid:ENSRNOG00000011024 AllianceGenome:RGD:1305755
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305755
    Summary
    Predicted to enable protein-cysteine S-palmitoyltransferase activity and zinc ion binding activity. Predicted to be involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation by host of viral process; and synaptic vesicle maturation. Predicted to be located in Golgi membrane and plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC20 (zinc finger DHHC-type palmitoyltransferase 20). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 174.7), Spleen (RPKM 144.6) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zdhhc20 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (36095624..36154546, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (31980057..32039006, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (38108886..38165765, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene Sin3A associated protein 18 Neighboring gene spindle and kinetochore associated complex subunit 3 Neighboring gene mitochondrial ribosomal protein L57 Neighboring gene uncharacterized LOC134482124 Neighboring gene mitochondrial calcium uptake 2 Neighboring gene uncharacterized LOC102550095 Neighboring gene fibroblast growth factor 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC156467

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables palmitoyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-cysteine S-palmitoyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in peptidyl-L-cysteine S-palmitoylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation by host of viral process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein palmitoylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptic vesicle maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    palmitoyltransferase ZDHHC20
    Names
    membrane-associated DHHC24 zinc finger protein
    probable palmitoyltransferase ZDHHC20
    zinc finger, DHHC domain containing 20
    zinc finger, DHHC-type containing 20
    NP_001034425.2
    XP_006252134.1
    XP_008768971.1
    XP_008768972.1
    XP_063130338.1
    XP_063130339.1
    XP_063130340.1
    XP_063130341.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039336.2NP_001034425.2  palmitoyltransferase ZDHHC20

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      Q2TGI6
      Conserved Domains (1) summary
      cl19890
      Location:16309
      DHHC; DHHC palmitoyltransferase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      36095624..36154546 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008770750.4XP_008768972.1  palmitoyltransferase ZDHHC20 isoform X4

      Conserved Domains (1) summary
      cl19890
      Location:75380
      zf-DHHC; DHHC palmitoyltransferase
    2. XM_063274270.1XP_063130340.1  palmitoyltransferase ZDHHC20 isoform X6

      UniProtKB/TrEMBL
      A0A8I6A7N7, A0JPI6
    3. XM_063274268.1XP_063130338.1  palmitoyltransferase ZDHHC20 isoform X3

      UniProtKB/TrEMBL
      F7FM28
      Related
      ENSRNOP00000014820.5, ENSRNOT00000014820.5
    4. XM_008770749.4XP_008768971.1  palmitoyltransferase ZDHHC20 isoform X2

      UniProtKB/TrEMBL
      F7FM28
      Conserved Domains (1) summary
      cl19890
      Location:75380
      zf-DHHC; DHHC palmitoyltransferase
    5. XM_006252072.5XP_006252134.1  palmitoyltransferase ZDHHC20 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AR22, Q2TGI6
      Related
      ENSRNOP00000059785.3, ENSRNOT00000063962.5
      Conserved Domains (1) summary
      cl19890
      Location:75380
      zf-DHHC; DHHC palmitoyltransferase
    6. XM_063274269.1XP_063130339.1  palmitoyltransferase ZDHHC20 isoform X5

      UniProtKB/TrEMBL
      A0JPI6
    7. XM_063274271.1XP_063130341.1  palmitoyltransferase ZDHHC20 isoform X7

      UniProtKB/TrEMBL
      A0JPI6, E9PT74