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    Zfas1 zinc finger, NFX1-type containing 1, antisense RNA 1 [ Mus musculus (house mouse) ]

    Gene ID: 68949, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfas1provided by MGI
    Official Full Name
    zinc finger, NFX1-type containing 1, antisense RNA 1provided by MGI
    Primary source
    MGI:MGI:1916199
    See related
    Ensembl:ENSMUSG00000074578 AllianceGenome:MGI:1916199
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfos1; 1500012F01Rik
    Summary
    Enables molecular function inhibitor activity and transmembrane transporter binding activity. Acts upstream of or within several processes, including negative regulation of ATPase-coupled calcium transmembrane transporter activity; negative regulation of calcium-dependent ATPase activity; and regulation of apoptotic process. Located in nucleus and sarcoplasmic reticulum. Orthologous to human ZFAS1 (ZNFX1 antisense RNA 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in liver E14 (RPKM 58.5), CNS E11.5 (RPKM 52.7) and 25 other tissues See more
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    Genomic context

    See Zfas1 in Genome Data Viewer
    Location:
    2 H3; 2 87.22 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (166904854..166907782)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (167062934..167065862)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene GLE1 RNA export mediator pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2656 Neighboring gene DEAD box helicase 27 Neighboring gene zinc finger, NFX1-type containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E6022 Neighboring gene predicted gene, 25878 Neighboring gene predicted gene, 23201 Neighboring gene small nucleolar RNA, C/D box 12 Neighboring gene STARR-seq mESC enhancer starr_06419 Neighboring gene predicted gene, 39984 Neighboring gene ribosomal protein L17 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Other Names

    • zinc finger, NFX1-type containing 1, opposite strand RNA 1

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular function inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables molecular function inhibitor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables transmembrane transporter binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cardiac muscle contraction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within cardiac muscle contraction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within mammary gland epithelial cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of ATPase-coupled calcium transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of ATPase-coupled calcium transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of calcium ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of calcium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of calcium-dependent ATPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of mammary gland epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of cardiac muscle cell apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of cardiac muscle cell apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of hypoxia-induced intrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in sarcoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in sarcoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_138563.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AI847202, AK005231, BF467288
      Related
      ENSMUST00000189909.9

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      166904854..166907782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001081005.1: Suppressed sequence

      Description
      NM_001081005.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.