U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Mup5 major urinary protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 17844, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mup5provided by MGI
    Official Full Name
    major urinary protein 5provided by MGI
    Primary source
    MGI:MGI:104974
    See related
    Ensembl:ENSMUSG00000058523 AllianceGenome:MGI:104974
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mup18
    Summary
    Predicted to enable insulin receptor activity and pheromone binding activity. Predicted to be involved in several processes, including regulation of gene expression; regulation of glucose metabolic process; and regulation of lipid metabolic process. Predicted to be located in cytosol and nucleus. Predicted to be active in extracellular space. Is expressed in nervous system and nose. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward liver adult (RPKM 589.5) See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mup5 in Genome Data Viewer
    Location:
    4 B3; 4 32.9 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (61749556..61753417, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (61831319..61858043, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene major urinary protein 19 Neighboring gene major urinary protein, pseudogene 16 Neighboring gene STARR-seq mESC enhancer starr_10399 Neighboring gene uncharacterized LOC118567368 Neighboring gene major urinary protein, pseudogene 23

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables insulin receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables pheromone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables small molecule binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in aerobic respiration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in cellular response to lipid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in energy reserve metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in glucose homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in heat generation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in insulin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in locomotor rhythm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrion organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of gluconeogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of insulin secretion involved in cellular response to glucose stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of lipid biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of lipid storage ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of glucose metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of lipid metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    major urinary protein 5
    Names
    MUP 5
    Mup V
    major urinary protein 18

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008649.2NP_032675.2  major urinary protein 5 precursor

      See identical proteins and their annotated locations for NP_032675.2

      Status: VALIDATED

      Source sequence(s)
      AL772344
      Consensus CDS
      CCDS18232.1
      UniProtKB/Swiss-Prot
      A2RSZ7, B5TE77, P11591
      Related
      ENSMUSP00000080908.3, ENSMUST00000082287.3
      Conserved Domains (1) summary
      cd19428
      Location:23180
      lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      61749556..61753417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)