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    CG7943 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43574, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7943provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039741
    Locus tag
    Dmel_CG7943
    See related
    AllianceGenome:FB:FBgn0039741
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7943
    Summary
    Predicted to enable NAD transmembrane transporter activity. Predicted to be active in mitochondrion. Is expressed in several structures, including adult head; embryonic/larval hemocyte; embryonic/larval midgut; embryonic/larval midgut primordium; and procrystal cell. Orthologous to human SLC25A51 (solute carrier family 25 member 51) and SLC25A52 (solute carrier family 25 member 52). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7943 in Genome Data Viewer
    Location:
    99D3-99D3; 3-100 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30046470..30048665)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25872192..25874387)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Serendipity delta Neighboring gene Ribosomal protein L32 Neighboring gene antisense RNA:CR44046 Neighboring gene uncharacterized protein Neighboring gene JIL-1 anchoring and stabilizing protein Neighboring gene spindle A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sex-specific pharmacokinetic response to phytoestrogens in Drosophila melanogaster. Sadova N, et al. Biomed Pharmacother, 2024 Jun. PMID 38663102
    2. EAST Organizes Drosophila Insulator Proteins in the Interchromosomal Nuclear Compartment and Modulates CP190 Binding to Chromatin. Golovnin A, et al. PLoS One, 2015. PMID 26489095, Free PMC Article
    3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
    4. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
    5. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables NAD transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7943-PA
    CG7943-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30046470..30048665
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170462.3 → NP_733341.1  uncharacterized protein Dmel_CG7943, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733341.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K483
      Related
      FBpp0084925
      Conserved Domains (1) summary
      pfam00153
      Location:235 → 322
      Mito_carr; Mitochondrial carrier protein

    2. NM_143509.4 → NP_651766.1  uncharacterized protein Dmel_CG7943, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651766.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K483
      Related
      FBpp0084926
      Conserved Domains (1) summary
      pfam00153
      Location:235 → 322
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K483 Q7K483

    Gene LinkOut

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