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    Sry-alpha Serendipity alpha [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43571, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sry-alphaprovided by FlyBase
    Official Full Name
    Serendipity alphaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003510
    Locus tag
    Dmel_CG17957
    See related
    AllianceGenome:FB:FBgn0003510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17957; Dmel\CG17957; ser; sry; sry alpha; Sry alpha; sry-a; sry-alpha; srya; sryalpha; Sryalpha
    Summary
    Predicted to enable actin filament binding activity and beta-catenin binding activity. Involved in actin filament organization and cellularization. Located in cleavage furrow and cytosol. Is expressed in germline cell; organism; and primordial germ cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Sry-alpha in Genome Data Viewer
    Location:
    99D3-99D3; 3-100 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30039719..30043071)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25866939..25868793)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ocnus Neighboring gene janus B Neighboring gene janus A Neighboring gene Serendipity beta Neighboring gene Serendipity delta Neighboring gene Ribosomal protein L32

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Development of an easy and cost-effective method for non-invasive genotyping of insects. Ali B, et al. PLoS One, 2019. PMID 31158235, Free PMC Article
    2. Cofilin-Mediated Actin Stress Response Is Maladaptive in Heat-Stressed Embryos. Figard L, et al. Cell Rep, 2019 Mar 26. PMID 30917306, Free PMC Article
    3. The nullo protein is a component of the actin-myosin network that mediates cellularization in Drosophila melanogaster embryos. Postner MA, et al. J Cell Sci, 1994 Jul. PMID 7983153
    4. A transgene-based, embryo-specific lethality system for insect pest management. Horn C, et al. Nat Biotechnol, 2003 Jan. PMID 12483222
    5. Actin cytoskeleton. Through the bottleneck. Theurkauf WE. Curr Biol, 1994 Jan 1. PMID 7922320

    See all (103) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables beta-catenin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellularization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellularization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellularization TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catenin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cleavage furrow IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serendipity alpha
    Names
    CG17957-PA
    CG17957-PB
    Sry-alpha-PA
    Sry-alpha-PB
    serendipity
    serendipity-alpha

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30039719..30043071
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316561.1 → NP_001303490.1  serendipity alpha, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P07666, Q9VAB4
      UniProtKB/TrEMBL
      A0A126GV23
      Conserved Domains (1) summary
      pfam05482
      Location:1 → 530
      Serendipity_A; Serendipity locus alpha protein (SRY-A)

    2. NM_079841.3 → NP_524580.1  serendipity alpha, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524580.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P07666, Q9VAB4
      UniProtKB/TrEMBL
      A0A126GV23
      Related
      FBpp0084923
      Conserved Domains (1) summary
      pfam05482
      Location:1 → 530
      Serendipity_A; Serendipity locus alpha protein (SRY-A)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A126GV23 A0A126GV23
    P07666.1 P07666

    Gene LinkOut

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