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    udd under-developed [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35781, updated on 9-Dec-2024

    Summary

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    Official Symbol
    uddprovided by FlyBase
    Official Full Name
    under-developedprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033261
    Locus tag
    Dmel_CG18316
    See related
    AllianceGenome:FB:FBgn0033261
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18316; Dmel\CG18316; Udd
    Summary
    Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus. Part of RNA polymerase transcription factor SL1 complex. Is expressed in embryonic/larval fat body; germarium; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See udd in Genome Data Viewer
    Location:
    44A4-44A4; 2-58 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8106385..8107373)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3993890..3994878)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene sandman Neighboring gene univalents only Neighboring gene Transmembrane protein 63 Neighboring gene Cullin 4 Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain Neighboring gene Nucleoporin 50kD Neighboring gene coilin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Participation of the piRNA pathway in recruiting a component of RNA polymerase I transcription initiation complex to germline cell nucleoli]. Fefelova EA, et al. Mol Biol (Mosk), 2017 Sep-Oct. PMID 29116069
    2. Nuclear architecture as an intrinsic regulator of Drosophila female germline stem cell maintenance. Duan T, et al. Curr Opin Insect Sci, 2020 Feb. PMID 32087561, Free PMC Article
    3. Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon. Fefelova EA, et al. Nucleic Acids Res, 2022 Jan 25. PMID 35037046, Free PMC Article
    4. The Drosophila ribosome protein S5 paralog RpS5b promotes germ cell and follicle cell differentiation during oogenesis. Jang S, et al. Development, 2021 Oct 1. PMID 34495316, Free PMC Article
    5. Blood-brain barrier defects associated with Rbp9 mutation. Kim J, et al. Mol Cells, 2010 Jan. PMID 20069381

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleolar large rRNA transcription by RNA polymerase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase transcription factor SL1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    under-developed
    Names
    CG18316-PA
    udd-PA
    under developed

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8106385..8107373
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136509.3 → NP_610353.1  under-developed [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610353.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z7A5, Q7JYM2
      Related
      FBpp0087860
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z7A5 A1Z7A5
    Q7JYM2 Q7JYM2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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