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    Sry-beta Serendipity beta [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43570, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sry-betaprovided by FlyBase
    Official Full Name
    Serendipity betaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003511
    Locus tag
    Dmel_CG7938
    See related
    AllianceGenome:FB:FBgn0003511
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7938; Dmel\CG7938; ser; sry; sry beta; sry-b; sry-beta; SrY-beta; sryb; srybeta; Srybeta
    Summary
    Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus and polytene chromosome interband. Is expressed in several structures, including endoderm anlage; female germline cell; gland; gonad; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Sry-beta in Genome Data Viewer
    Location:
    99D3-99D3; 3-100 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30039719..30043071)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25865441..25866753)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ocnus Neighboring gene janus B Neighboring gene janus A Neighboring gene Serendipity alpha Neighboring gene Serendipity delta Neighboring gene Ribosomal protein L32

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic targets of the serendipity beta and delta zinc finger proteins and their respective DNA recognition sites. Payre F, et al. EMBO J, 1991 Sep. PMID 1868833, Free PMC Article
    2. Zinc fingers and other domains cooperate in binding of Drosophila sry beta and delta proteins at specific chromosomal sites. Noselli S, et al. Mol Cell Biol, 1992 Feb. PMID 1732741, Free PMC Article
    3. The closely related Drosophila sry beta and sry delta zinc finger proteins show differential embryonic expression and distinct patterns of binding sites on polytene chromosomes. Payre F, et al. Development, 1990 Sep. PMID 2081456
    4. The spatial distribution of a blastoderm stage-specific mRNA from the serendipity locus of Drosophila melanogaster. James AA, et al. Dev Biol, 1986 Dec. PMID 3098598
    5. Blastoderm-specific and read-through transcription of the sry alpha gene transformed into the Drosophila genome. Vincent A, et al. Dev Biol, 1986 Dec. PMID 3098599

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in polytene chromosome interband IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serendipity beta
    Names
    CG7938-PA
    CG7938-PB
    Sry-beta-PA
    Sry-beta-PB
    serendipity

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30039719..30043071
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316522.1 → NP_001303451.1  serendipity beta, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P07665, Q9VAB5
      UniProtKB/TrEMBL
      A0A126GV25
      Conserved Domains (3) summary
      sd00017
      Location:231 → 251
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:288 → 303
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:315 → 337
      zf-C2H2; Zinc finger, C2H2 type

    2. NM_079840.3 → NP_524579.1  serendipity beta, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524579.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P07665, Q9VAB5
      UniProtKB/TrEMBL
      A0A126GV25
      Related
      FBpp0084922
      Conserved Domains (3) summary
      sd00017
      Location:231 → 251
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:288 → 303
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:315 → 337
      zf-C2H2; Zinc finger, C2H2 type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A126GV25 A0A126GV25
    P07665.2 P07665

    Gene LinkOut

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