U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Klf9 Kruppel-like transcription factor 9 [ Mus musculus (house mouse) ]

    Gene ID: 16601, updated on 9-Dec-2024

    Summary

    Official Symbol
    Klf9provided by MGI
    Official Full Name
    Kruppel-like transcription factor 9provided by MGI
    Primary source
    MGI:MGI:1333856
    See related
    Ensembl:ENSMUSG00000033863 AllianceGenome:MGI:1333856
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bteb1; BTEB-1; Gm9971; 2310051E17Rik
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within embryo implantation; progesterone receptor signaling pathway; and regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and skeleton. Orthologous to human KLF9 (KLF transcription factor 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in lung adult (RPKM 44.8), adrenal adult (RPKM 44.1) and 21 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Klf9 in Genome Data Viewer
    Location:
    19 B; 19 17.9 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (23118590..23145493)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (23141226..23168129)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel, subfamily M, member 3 Neighboring gene RIKEN cDNA C330002G04 gene Neighboring gene STARR-seq mESC enhancer starr_45752 Neighboring gene STARR-seq mESC enhancer starr_45755 Neighboring gene STARR-seq mESC enhancer starr_45757 Neighboring gene STARR-seq mESC enhancer starr_45759 Neighboring gene STARR-seq mESC enhancer starr_45760 Neighboring gene RIKEN cDNA 2410080I02 gene Neighboring gene STARR-seq mESC enhancer starr_45763 Neighboring gene STARR-positive B cell enhancer ABC_E4273 Neighboring gene STARR-seq mESC enhancer starr_45766 Neighboring gene STARR-seq mESC enhancer starr_45769 Neighboring gene STARR-seq mESC enhancer starr_45772 Neighboring gene microRNA 1192 Neighboring gene STARR-positive B cell enhancer mm9_chr19:23348377-23348678 Neighboring gene structural maintenance of chromosomes 5 Neighboring gene predicted gene, 33950 Neighboring gene predicted gene, 24263

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    Krueppel-like factor 9
    Names
    BTE-binding protein 1
    GC-box-binding protein 1
    Kruppel-like factor 9
    basic transcription element binding protein 1
    transcription factor BTEB1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010638.5NP_034768.2  Krueppel-like factor 9

      See identical proteins and their annotated locations for NP_034768.2

      Status: VALIDATED

      Source sequence(s)
      AC121973
      Consensus CDS
      CCDS29706.1
      UniProtKB/Swiss-Prot
      O35739
      UniProtKB/TrEMBL
      Q8CEC4
      Related
      ENSMUSP00000045639.2, ENSMUST00000036884.3
      Conserved Domains (2) summary
      COG5048
      Location:78234
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:145167
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      23118590..23145493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)