H2al1m H2A histone family member L1M [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: H2al1mprovided by MGI
Official Full Name: H2A histone family member L1Mprovided by MGI
Primary source: MGI:MGI:1923633
See related: Ensembl:ENSMUSG00000100200 AllianceGenome:MGI:1923633
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: H2al1; 1700012L04Rik
Summary: Predicted to be a structural constituent of chromatin. Predicted to be involved in heterochromatin formation. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H2AL3 (H2A.L variant histone 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: X A1.1; X 4.22 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (9150003..9150527)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (9283764..9284288)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

H2AL1 and H2AL2, specifically mark the pericentric regions in condensing spermatids and participate in the formation of new nucleoprotein structures
Title: Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables structural constituent of chromatin	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in heterochromatin formation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of nucleosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: histone variant H2al1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_029588.3 → NP_083864.1 histone variant H2al1

See identical proteins and their annotated locations for NP_083864.1

Status: PROVISIONAL

Source sequence(s)

AK005922

Consensus CDS

CCDS40856.1

UniProtKB/TrEMBL

B1AV31, Q9DAD9

Related

ENSMUSP00000073605.4, ENSMUST00000073949.4

Conserved Domains (1) summary

cl23907
Location:50 → 94

H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...