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    Utp6 UTP6 small subunit processome component [ Mus musculus (house mouse) ]

    Gene ID: 216987, updated on 9-Dec-2024

    Summary

    Official Symbol
    Utp6provided by MGI
    Official Full Name
    UTP6 small subunit processome componentprovided by MGI
    Primary source
    MGI:MGI:2445193
    See related
    Ensembl:ENSMUSG00000035575 AllianceGenome:MGI:2445193
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HCA66; 4732497O03Rik
    Summary
    Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in chromosome and nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Is expressed in several structures, including brain; branchial arch; future forebrain; heart; and inner ear. Orthologous to human UTP6 (UTP6 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 15.0), placenta adult (RPKM 9.6) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Utp6 in Genome Data Viewer
    Location:
    11 B5; 11 47.29 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (79824782..79853213, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (79933956..79962387, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 24454 Neighboring gene phosphoglycerate mutase 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E907 Neighboring gene STARR-seq mESC enhancer starr_30132 Neighboring gene predicted gene, 30875 Neighboring gene SUZ12 polycomb repressive complex 2 subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC25509

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables snoRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Pwp2p-containing subcomplex of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    U3 small nucleolar RNA-associated protein 6 homolog
    Names
    UTP6, small subunit (SSU) processome component, homolog
    hepatocellular carcinoma-associated antigen 66
    multiple hat domains protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144826.3NP_659075.1  U3 small nucleolar RNA-associated protein 6 homolog

      See identical proteins and their annotated locations for NP_659075.1

      Status: PROVISIONAL

      Source sequence(s)
      AK029151
      Consensus CDS
      CCDS25124.1
      UniProtKB/Swiss-Prot
      Q8CH76, Q8VCY6
      Related
      ENSMUSP00000046643.6, ENSMUST00000043152.6
      Conserved Domains (2) summary
      COG5191
      Location:1222
      COG5191; Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat [General function prediction only]
      pfam08640
      Location:981
      U3_assoc_6; U3 small nucleolar RNA-associated protein 6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      79824782..79853213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)