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    Ebf3 early B cell factor 3 [ Mus musculus (house mouse) ]

    Gene ID: 13593, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ebf3provided by MGI
    Official Full Name
    early B cell factor 3provided by MGI
    Primary source
    MGI:MGI:894289
    See related
    Ensembl:ENSMUSG00000010476 AllianceGenome:MGI:894289
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    O/E-2; mKIAA4201; 3110018A08Rik
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; limb; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in hypotonia, ataxia, and delayed development syndrome. Orthologous to human EBF3 (EBF transcription factor 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E14 (RPKM 24.6), limb E14.5 (RPKM 23.6) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ebf3 in Genome Data Viewer
    Location:
    7 F3- F4; 7 82.26 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (136795400..136924528, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (137193671..137322805, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene O-6-methylguanine-DNA methyltransferase Neighboring gene predicted gene, 39108 Neighboring gene STARR-seq mESC enhancer starr_20380 Neighboring gene STARR-seq mESC enhancer starr_20381 Neighboring gene predicted gene, 30061 Neighboring gene STARR-seq mESC enhancer starr_20382 Neighboring gene predicted gene 10578 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:144481070-144481271 Neighboring gene STARR-seq mESC enhancer starr_20383 Neighboring gene RIKEN cDNA 9430038I01 gene Neighboring gene STARR-positive B cell enhancer ABC_E2852 Neighboring gene nucleolin pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (6) 
    • Targeted (6)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA4201

    General protein information

    Preferred Names
    transcription factor COE3
    Names
    EBF-3
    OE-2
    Olf-1/EBF-like 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113414.2NP_001106885.1  transcription factor COE3 isoform 2

      See identical proteins and their annotated locations for NP_001106885.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternative, in-frame donor splice site at one of the internal coding exons, compared to transcript variant 1. This results in a shorter isoform (2) that is missing a 9 aa segment, compared to isoform 1.
      Source sequence(s)
      AC135639
      Consensus CDS
      CCDS52423.1
      UniProtKB/TrEMBL
      Q6NXL3, Q8CBL7
      Related
      ENSMUSP00000132563.3, ENSMUST00000169486.9
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    2. NM_001113415.2NP_001106886.1  transcription factor COE3 isoform 1

      See identical proteins and their annotated locations for NP_001106886.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1)
      Source sequence(s)
      AC135639
      Consensus CDS
      CCDS52422.1
      UniProtKB/Swiss-Prot
      O08791, O08793
      UniProtKB/TrEMBL
      Q8CBL7
      Related
      ENSMUSP00000147829.2, ENSMUST00000210774.2
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    3. NM_010096.4NP_034226.1  transcription factor COE3 isoform 3

      See identical proteins and their annotated locations for NP_034226.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate, in-frame donor acceptor site at the penultimate coding exon, and an alternative, in-frame donor splice site at one of the internal coding exons, compared to transcript variant 1. This results in a shorter isoform (3) that is missing 36 aa and 9 aa segments, compared to isoform 1.
      Source sequence(s)
      AC135639
      Consensus CDS
      CCDS21946.1
      UniProtKB/TrEMBL
      Q5DTH8
      Related
      ENSMUSP00000033378.6, ENSMUST00000033378.13
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      136795400..136924528 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152643.1XP_036008536.1  transcription factor COE3 isoform X1

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    2. XM_036152647.1XP_036008540.1  transcription factor COE3 isoform X3

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    3. XM_036152646.1XP_036008539.1  transcription factor COE3 isoform X3

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    4. XM_036152645.1XP_036008538.1  transcription factor COE3 isoform X1

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    5. XM_036152644.1XP_036008537.1  transcription factor COE3 isoform X1

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    6. XM_006507334.3XP_006507397.1  transcription factor COE3 isoform X10

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    7. XM_006507336.3XP_006507399.1  transcription factor COE3 isoform X14

      See identical proteins and their annotated locations for XP_006507399.1

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    8. XM_006507331.3XP_006507394.1  transcription factor COE3 isoform X2

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    9. XM_030242085.2XP_030097945.1  transcription factor COE3 isoform X1

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    10. XM_030242086.2XP_030097946.1  transcription factor COE3 isoform X4

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    11. XM_030242094.2XP_030097954.1  transcription factor COE3 isoform X17

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
    12. XM_030242092.2XP_030097952.1  transcription factor COE3 isoform X13

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    13. XM_006507333.3XP_006507396.1  transcription factor COE3 isoform X6

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    14. XM_030242095.2XP_030097955.1  transcription factor COE3 isoform X18

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    15. XM_011241672.3XP_011239974.1  transcription factor COE3 isoform X15

      See identical proteins and their annotated locations for XP_011239974.1

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    16. XM_006507332.3XP_006507395.1  transcription factor COE3 isoform X3

      UniProtKB/TrEMBL
      Q8CBL7
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    17. XM_030242087.2XP_030097947.1  transcription factor COE3 isoform X5

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    18. XM_030242088.2XP_030097948.1  transcription factor COE3 isoform X7

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    19. XM_030242093.2XP_030097953.1  transcription factor COE3 isoform X16

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    20. XM_036152651.1XP_036008544.1  transcription factor COE3 isoform X21

      Conserved Domains (3) summary
      cd01175
      Location:47131
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16423
      Location:132175
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
      cl17007
      Location:140
      COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
    21. XM_036152650.1XP_036008543.1  transcription factor COE3 isoform X20

      Conserved Domains (3) summary
      cd01175
      Location:56140
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16423
      Location:141184
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
      cl17007
      Location:140
      COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
    22. XM_036152652.1XP_036008545.1  transcription factor COE3 isoform X22

      Conserved Domains (3) summary
      cd01175
      Location:47131
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16423
      Location:132175
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
      cl17007
      Location:140
      COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
    23. XM_030242090.2XP_030097950.1  transcription factor COE3 isoform X9

      UniProtKB/TrEMBL
      Q6NXL3, Q8CBL7
      Related
      ENSMUSP00000101724.4, ENSMUST00000106118.10
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    24. XM_006507335.3XP_006507398.1  transcription factor COE3 isoform X11

      See identical proteins and their annotated locations for XP_006507398.1

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    25. XM_036152653.1XP_036008546.1  transcription factor COE3 isoform X23

      UniProtKB/TrEMBL
      Q3UUB6
      Related
      ENSMUSP00000147512.2, ENSMUST00000209578.2
      Conserved Domains (3) summary
      cd01175
      Location:47131
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16423
      Location:132175
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
      cl17007
      Location:140
      COE_DBD; Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain
    26. XM_030242091.2XP_030097951.1  transcription factor COE3 isoform X12

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    27. XM_030242089.2XP_030097949.1  transcription factor COE3 isoform X8

      UniProtKB/TrEMBL
      Q5DTH8
      Conserved Domains (3) summary
      cd01175
      Location:254338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain
    28. XM_006507337.5XP_006507400.1  transcription factor COE3 isoform X19

      Conserved Domains (3) summary
      cd01175
      Location:263347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain