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    nompA no mechanoreceptor potential A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 45587, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nompAprovided by FlyBase
    Official Full Name
    no mechanoreceptor potential Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0016047
    Locus tag
    Dmel_CG13207
    See related
    AllianceGenome:FB:FBgn0016047
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13207; Dmel\CG13207; nomp; Nomp-A; NompA; NOMPA; y
    Summary
    Involved in dendrite morphogenesis; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and sensory perception of sound. Located in extracellular matrix. Is expressed in several structures, including embryonic head sensory system; embryonic labial sensory complex; mechanosensory sensory organ; sensory nervous system primordium; and sensory organ cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See nompA in Genome Data Viewer
    Location:
    47F1-47F1; 2-64 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11310335..11318676, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7197840..7206181, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Farnesyl pyrophosphate synthase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 47b Neighboring gene shavenoid

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Power gain exhibited by motile mechanosensory neurons in Drosophila ears. Göpfert MC, et al. Proc Natl Acad Sci U S A, 2005 Jan 11. PMID 15623551, Free PMC Article
    2. Functional Interaction Between Drosophila Olfactory Sensory Neurons and Their Support Cells. Prelic S, et al. Front Cell Neurosci, 2021. PMID 35069116, Free PMC Article
    3. Motion generation by Drosophila mechanosensory neurons. Göpfert MC, et al. Proc Natl Acad Sci U S A, 2003 Apr 29. PMID 12642657, Free PMC Article
    4. More whistles and bells for fly hearing. Walker RG. Proc Natl Acad Sci U S A, 2003 May 13. PMID 12732710, Free PMC Article
    5. Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila. Todi SV, et al. Curr Biol, 2005 May 10. PMID 15886106, Free PMC Article

    See all (72) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NompA gene is required for nonsense-mediated mRNA decay pathway.
      Title: Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in dendrite morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of mechanical stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of sound IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    no mechanoreceptor potential A
    Names
    CG13207-PA
    CG13207-PB
    CG13207-PC
    CG13207-PD
    CG13207-PF
    nompA-PA
    nompA-PB
    nompA-PC
    nompA-PD
    nompA-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11310335..11318676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299383.1 → NP_001286312.1  no mechanoreceptor potential A, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286312.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LF37, Q9BMD5
      Conserved Domains (3) summary
      smart00241
      Location:774 → 1013
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:349 → 424
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
      cl42516
      Location:500 → 656
      dnaA; chromosomal replication initiator protein DnaA

    2. NM_165821.4 → NP_725030.2  no mechanoreceptor potential A, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725030.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8J3, Q9BMD4
      Related
      FBpp0088406
      Conserved Domains (2) summary
      smart00241
      Location:1025 → 1264
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:349 → 424
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...

    3. NM_080092.4 → NP_524831.2  no mechanoreceptor potential A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524831.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8J4, Q9BMD5
      Related
      FBpp0088407

    4. NM_206096.3 → NP_995818.1  no mechanoreceptor potential A, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995818.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8J3, Q9BMD4
      Conserved Domains (2) summary
      smart00241
      Location:1025 → 1264
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:349 → 424
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...

    5. NM_165822.4 → NP_725031.2  no mechanoreceptor potential A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725031.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8J4, Q9BMD5
      Related
      FBpp0088405
      Conserved Domains (2) summary
      smart00241
      Location:1025 → 1264
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:349 → 424
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LF37 A0A0B4LF37
    A1Z8J3 A1Z8J3
    A1Z8J4 A1Z8J4
    Q9BMD4 Q9BMD4
    Q9BMD5 Q9BMD5

    Gene LinkOut

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