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    CG11788 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37295, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11788provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034495
    Locus tag
    Dmel_CG11788
    See related
    AllianceGenome:FB:FBgn0034495
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11788
    Summary
    Predicted to be involved in maintenance of mitotic sister chromatid cohesion and regulation of DNA replication. Predicted to be located in chromatin and nucleoplasm. Predicted to be part of Ctf18 RFC-like complex. Predicted to be active in chromosome, centromeric region. Orthologous to human DSCC1 (DNA replication and sister chromatid cohesion 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11788 in Genome Data Viewer
    Location:
    56F11-56F14; 2-90 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20274597..20276142)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16162102..16163647)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43812 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Mitochondrial phosphate carrier protein 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RBF binding to both canonical E2F targets and noncanonical targets depends on functional dE2F/dDP complexes. Korenjak M, et al. Mol Cell Biol, 2012 Nov. PMID 22927638, Free PMC Article
    2. Unbiased Boolean analysis of public gene expression data for cell cycle gene identification. Dabydeen SA, et al. Mol Biol Cell, 2019 Jul 1. PMID 31091168, Free PMC Article
    3. Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity. Spresser CR, et al. J Genet, 2008 Aug. PMID 18776638
    4. Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Dimova DK, et al. Genes Dev, 2003 Sep 15. PMID 12975318, Free PMC Article
    5. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in maintenance of mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic sister chromatid cohesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA replication ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of Ctf18 RFC-like complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Ctf18 RFC-like complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in chromosome, centromeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11788-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20274597..20276142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137622.3 → NP_611466.2  uncharacterized protein Dmel_CG11788 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611466.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V3Z5
      Conserved Domains (1) summary
      pfam09724
      Location:54 → 392
      DUF2036; Uncharacterized conserved protein (DUF2036)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V3Z5 Q4V3Z5

    Gene LinkOut

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