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    CG3500 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37697, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG3500provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034849
    Locus tag
    Dmel_CG3500
    See related
    AllianceGenome:FB:FBgn0034849
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT03803; Dmel\CG3500
    Summary
    Predicted to enable COPII receptor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in membrane. Predicted to be active in COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum membrane. Is expressed in adult head and organism. Orthologous to human TEX261 (testis expressed 261). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3500 in Genome Data Viewer
    Location:
    59D8-59D8; 2-102 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23356372..23357565, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19243895..19245088, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Ribose-5-phosphate isomerase Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44168 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Scrutinizing the human TEX genes in the context of human male infertility. Sieper MH, et al. Andrology, 2024 Mar. PMID 37594251
    2. Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity. Butzlaff M, et al. Hum Mol Genet, 2015 Jul 1. PMID 25794683
    3. A Drosophila in vivo screen identifies store-operated calcium entry as a key regulator of adiposity. Baumbach J, et al. Cell Metab, 2014 Feb 4. PMID 24506874
    4. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables COPII receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables COPII receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3500-PA
    CG3500-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23356372..23357565 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137939.3 → NP_611783.1  uncharacterized protein Dmel_CG3500, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611783.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T924, Q9W1R8
      Related
      FBpp0071947
      Conserved Domains (1) summary
      pfam04148
      Location:1 → 187
      Erv26; Transmembrane adaptor Erv26

    2. NM_001274223.2 → NP_001261152.1  uncharacterized protein Dmel_CG3500, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261152.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T924, Q9W1R8
      Conserved Domains (1) summary
      pfam04148
      Location:1 → 187
      Erv26; Transmembrane adaptor Erv26
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T924 Q8T924
    Q9W1R8 Q9W1R8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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