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    CG3894 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37959, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3894provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035059
    Locus tag
    Dmel_CG3894
    See related
    AllianceGenome:FB:FBgn0035059
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9197; Dmel\CG3894
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in intracellular signal transduction. Orthologous to human NEURL2 (neuralized E3 ubiquitin protein ligase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3894 in Genome Data Viewer
    Location:
    60E1-60E1; 2-107 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24763167..24766750)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20650690..20654273)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene spatzle 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glutathione S transferase E12 Neighboring gene Epidermal growth factor receptor pathway substrate clone 15 Neighboring gene antisense RNA:CR44067 Neighboring gene eggless

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Euchromatic transposon insertions trigger production of novel Pi- and endo-siRNAs at the target sites in the drosophila germline. Shpiz S, et al. PLoS Genet, 2014 Feb. PMID 24516406, Free PMC Article
    2. Identification of expressed transposable element insertions in the sequenced genome of Drosophila melanogaster. Deloger M, et al. Gene, 2009 Jun 15. PMID 19332112
    3. Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster. Schrider DR, et al. Genome Res, 2011 Dec. PMID 22135405, Free PMC Article
    4. A genome-wide RNAi screen reveals multiple regulators of caspase activation. Yi CH, et al. J Cell Biol, 2007 Nov 19. PMID 17998402, Free PMC Article
    5. Stonewalling Drosophila stem cell differentiation by epigenetic controls. Maines JZ, et al. Development, 2007 Apr. PMID 17344229

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 24763666-24765583 mobile_element_type = transposon:G2{}CG3894[iso-1]

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3894-PC
    dmNeural-like

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24763167..24766750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138119.7 → NP_611963.5  uncharacterized protein Dmel_CG3894 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611963.5

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W112
      Conserved Domains (2) summary
      cd03717
      Location:283 → 321
      SOCS_SOCS_like; SOCS (suppressors of cytokine signaling) box of SOCS-like proteins. The CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. These intracellular proteins regulate the responses of immune cells to ...
      cd12887
      Location:64 → 280
      SPRY_NHR_like; SPRY domain in neuralized homology repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MRU1 Q8MRU1
    Q9W112 Q9W112

    Gene LinkOut

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