CG10587 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG10587provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0037039
Locus tag: Dmel_CG10587
See related: AllianceGenome:FB:FBgn0037039
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG10587; SP167
Summary: Enables serine hydrolase activity. Involved in sexual reproduction. Located in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 78A1-78A1; 3-47 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (20961537..20962555, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (20954637..20955655, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables serine hydrolase activity	HDA more info	PubMed
enables serine-type endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase activity	ISM Inferred from Sequence Model more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info
involved_in proteolysis	ISM Inferred from Sequence Model more info	PubMed
involved_in sexual reproduction	HEP more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	HDA more info	PubMed

General protein information

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Preferred Names: uncharacterized protein

Names: CG10587-PA; CG10587-PC; CG10587-PD

NP_001137989.2

EC 3.4.21.-

NP_001287136.1

EC 3.4.21.-

NP_649273.1

EC 3.4.21.-

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_037436.4 Reference assembly

Range

20961537..20962555 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_141016.2 → NP_649273.1 uncharacterized protein Dmel_CG10587, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_649273.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9VP92

Related

FBpp0077989

Conserved Domains (2) summary

smart00020
Location:45 → 265

Tryp_SPc; Trypsin-like serine protease

cd00190
Location:46 → 267

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
NM_001144517.2 → NP_001137989.2 uncharacterized protein Dmel_CG10587, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001137989.2

Status: REVIEWED

UniProtKB/TrEMBL

B7Z091

Conserved Domains (2) summary

smart00020
Location:45 → 278

Tryp_SPc; Trypsin-like serine protease

cd00190
Location:46 → 280

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
NM_001300207.1 → NP_001287136.1 uncharacterized protein Dmel_CG10587, isoform D [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001287136.1

Status: REVIEWED

UniProtKB/TrEMBL

F3YDD1, X2JCP6

Conserved Domains (1) summary

cl21584
Location:46 → 200

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...