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    CG4730 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43099, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4730provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039355
    Locus tag
    Dmel_CG4730
    See related
    AllianceGenome:FB:FBgn0039355
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4730
    Summary
    Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in organism. Orthologous to human MAZ (MYC associated zinc finger protein) and ZNF692 (zinc finger protein 692). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4730 in Genome Data Viewer
    Location:
    96E9-96E9; 3-88 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25677072..25678682, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21502794..21504404, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45208 Neighboring gene Ras association domain family member 8 Neighboring gene Leucine-rich repeat-containing G protein-coupled receptor 3 Neighboring gene long non-coding RNA:CR45225 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma Neighboring gene Ribosomal protein L27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanisms of CP190 Interaction with Architectural Proteins in Drosophila Melanogaster. Sabirov M, et al. Int J Mol Sci, 2021 Nov 17. PMID 34830280, Free PMC Article
    2. Global analysis of target genes of 21 members of the ZAD transcription factor family in Drosophila melanogaster. Krystel J, et al. Gene, 2013 Jan 10. PMID 23085320, Free PMC Article
    3. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    4. Genome-Wide Mapping Targets of the Metazoan Chromatin Remodeling Factor NURF Reveals Nucleosome Remodeling at Enhancers, Core Promoters and Gene Insulators. Kwon SY, et al. PLoS Genet, 2016 Apr. PMID 27046080, Free PMC Article
    5. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4730-PA
    CG4730-PB
    CG4730-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25677072..25678682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143156.4 → NP_651413.1  uncharacterized protein Dmel_CG4730, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651413.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBN9
      Related
      FBpp0084308
      Conserved Domains (2) summary
      sd00017
      Location:240 → 260
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:46 → 124
      zf-AD; Zinc-finger associated domain (zf-AD)

    2. NM_001276036.1 → NP_001262965.1  uncharacterized protein Dmel_CG4730, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262965.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBN9
      Conserved Domains (2) summary
      sd00017
      Location:240 → 260
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:46 → 124
      zf-AD; Zinc-finger associated domain (zf-AD)

    3. NM_001276035.1 → NP_001262964.1  uncharacterized protein Dmel_CG4730, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262964.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHV9
      Conserved Domains (2) summary
      sd00017
      Location:182 → 202
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:3 → 66
      zf-AD; Zinc-finger associated domain (zf-AD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KHV9 A0A0B4KHV9
    Q9VBN9 Q9VBN9

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