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    CG3544 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33252, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3544provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031279
    Locus tag
    Dmel_CG3544
    See related
    AllianceGenome:FB:FBgn0031279
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3544
    Summary
    Predicted to enable D-xylulokinase activity. Predicted to be involved in carbohydrate phosphorylation and xylulose metabolic process. Predicted to be located in extracellular exosome. Predicted to be active in cytosol. Is expressed in embryonic brain; larval nervous system; and larval ventral nerve cord. Orthologous to human XYLB (xylulokinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3544 in Genome Data Viewer
    Location:
    21E2-21E2; 2-1.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (784336..788776)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (784336..788776)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 21a Neighboring gene Protein kinase, cGMP-dependent at 21D Neighboring gene long non-coding RNA:CR45259 Neighboring gene Nnf1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aberrant splicing of an alternative exon in the Drosophila troponin-T gene affects flight muscle development. Nongthomba U, et al. Genetics, 2007 Sep. PMID 17603127, Free PMC Article
    2. Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease. Huichalaf CH, et al. Hum Mol Genet, 2019 Jun 15. PMID 30753434, Free PMC Article
    3. Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. Doggett K, et al. Dev Biol, 2011 Jul 15. PMID 21570388, Free PMC Article
    4. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
    5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables D-xylulokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-xylulokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-xylose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in xylulose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular exosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3544-PA
    CG3544-PB
    NP_001259842.1
    NP_608543.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      784336..788776
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272913.1 → NP_001259842.1  uncharacterized protein Dmel_CG3544, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259842.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPT2
      Conserved Domains (2) summary
      cd07776
      Location:13 → 493
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases
      TIGR01312
      Location:15 → 494
      XylB; D-xylulose kinase

    2. NM_134699.3 → NP_608543.1  uncharacterized protein Dmel_CG3544, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608543.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPT2
      Related
      FBpp0077672
      Conserved Domains (2) summary
      cd07776
      Location:13 → 493
      FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases
      TIGR01312
      Location:15 → 494
      XylB; D-xylulose kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPT2 Q9VPT2

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