U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nudt13 nudix hydrolase 13 [ Mus musculus (house mouse) ]

    Gene ID: 67725, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nudt13provided by MGI
    Official Full Name
    nudix hydrolase 13provided by MGI
    Primary source
    MGI:MGI:1914975
    See related
    Ensembl:ENSMUSG00000021809 AllianceGenome:MGI:1914975
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933433B15Rik
    Summary
    Enables NADH pyrophosphatase activity. Involved in NADH metabolic process and NADP catabolic process. Located in mitochondrion. Is expressed in brain; endocrine gland; male reproductive gland or organ; metanephros; and trachea. Orthologous to human NUDT13 (nudix hydrolase 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 3.1), bladder adult (RPKM 3.1) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nudt13 in Genome Data Viewer
    Location:
    14 A3; 14 11.5 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (20344709..20367652)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (20294679..20317584)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene potassium channel, subfamily K, member 17 pseudogene Neighboring gene potassium channel, subfamily K, member 16 Neighboring gene STARR-positive B cell enhancer ABC_E1470 Neighboring gene ecdysoneless cell cycle regulator Neighboring gene STARR-seq mESC enhancer starr_36108 Neighboring gene STARR-positive B cell enhancer ABC_E7295 Neighboring gene family with sequence similarity 149, member B Neighboring gene predicted gene, 30054

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    General protein information

    Preferred Names
    NAD(P)H pyrophosphatase NUDT13, mitochondrial
    Names
    nucleoside diphosphate-linked moiety X motif 13
    nudix (nucleoside diphosphate linked moiety X)-type motif 13
    nudix motif 13
    NP_001346797.1
    NP_001346798.1
    NP_001346799.1
    NP_080617.2
    XP_006519526.1
    XP_006519531.1
    XP_006519534.1
    XP_011243461.1
    XP_011243466.1
    XP_030103834.1
    XP_036014722.1
    XP_036014723.1
    XP_036014724.1
    XP_036014725.1
    XP_036014726.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359868.1NP_001346797.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC159106, AK014204, AK161922, BB838132, BE987250, BY034640
      UniProtKB/TrEMBL
      Q80VI7
      Conserved Domains (1) summary
      COG2816
      Location:49360
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    2. NM_001359869.1NP_001346798.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC159106, AK014204, AK161922, BB838132, BE987250, BY034640
      Conserved Domains (2) summary
      pfam09296
      Location:63179
      NUDIX-like; NADH pyrophosphatase-like rudimentary NUDIX domain
      pfam09297
      Location:183212
      zf-NADH-PPase; NADH pyrophosphatase zinc ribbon domain
    3. NM_001359870.1NP_001346799.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC159106, AK014204, AK161922, BB838132, BE987250, BQ749237
      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    4. NM_026341.3NP_080617.2  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform 2

      See identical proteins and their annotated locations for NP_080617.2

      Status: VALIDATED

      Source sequence(s)
      AC159106, AK014204, AK161922, BB838132, BE987250, BY034640
      Consensus CDS
      CCDS36815.1
      UniProtKB/Swiss-Prot
      Q8JZU0, Q9CXN4
      UniProtKB/TrEMBL
      Q80VI7
      Related
      ENSMUSP00000022343.5, ENSMUST00000022343.6
      Conserved Domains (4) summary
      COG2816
      Location:32343
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
      cd03429
      Location:200343
      NADH_pyrophosphatase; NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for ...
      pfam09296
      Location:46162
      NUDIX-like; NADH pyrophosphatase-like rudimentary NUDIX domain
      pfam09297
      Location:166195
      zf-NADH-PPase; NADH pyrophosphatase zinc ribbon domain

    RNA

    1. NR_153363.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159106, AK017031, AK161922, BB838132, BE987250
      Related
      ENSMUST00000225722.2
    2. NR_153364.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159106, AK017031, AK161922, BB838132, BE987250

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      20344709..20367652
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158831.1XP_036014724.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X4

      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    2. XM_036158829.1XP_036014722.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X1

      UniProtKB/TrEMBL
      Q80VI7
      Conserved Domains (1) summary
      COG2816
      Location:49360
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    3. XM_011245159.2XP_011243461.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_011243461.1

      UniProtKB/TrEMBL
      Q80VI7
      Conserved Domains (1) summary
      COG2816
      Location:49360
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    4. XM_030247974.2XP_030103834.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X4

      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    5. XM_011245164.2XP_011243466.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X4

      See identical proteins and their annotated locations for XP_011243466.1

      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    6. XM_006519463.3XP_006519526.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X2

      See identical proteins and their annotated locations for XP_006519526.1

      UniProtKB/TrEMBL
      Q80VI7
      Conserved Domains (1) summary
      COG2816
      Location:36347
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    7. XM_006519468.5XP_006519531.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X4

      See identical proteins and their annotated locations for XP_006519531.1

      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    8. XM_036158830.1XP_036014723.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A286YE01
      Related
      ENSMUSP00000153437.2, ENSMUST00000223941.2
      Conserved Domains (2) summary
      pfam09296
      Location:47162
      NUDIX-like; NADH pyrophosphatase-like rudimentary NUDIX domain
      pfam09297
      Location:166195
      zf-NADH-PPase; NADH pyrophosphatase zinc ribbon domain
    9. XM_036158833.1XP_036014726.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X4

      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    10. XM_006519471.4XP_006519534.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X4

      See identical proteins and their annotated locations for XP_006519534.1

      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]
    11. XM_036158832.1XP_036014725.1  NAD(P)H pyrophosphatase NUDT13, mitochondrial isoform X4

      Conserved Domains (1) summary
      COG2816
      Location:1217
      NPY1; NADH pyrophosphatase NudC, Nudix superfamily [Nucleotide transport and metabolism]

    RNA

    1. XR_004938441.1 RNA Sequence