Cog3 Component of oligomeric golgi complex 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Cog3provided by FlyBase
Official Full Name: Component of oligomeric golgi complex 3provided by FlyBase
Primary source: FLYBASE:FBgn0031536
Locus tag: Dmel_CG3248
See related: AllianceGenome:FB:FBgn0031536
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG 3248; CG3248; COG3; dCOG3; Dmel\CG3248; SEC34
Summary: Involved in dsRNA transport and male meiosis cytokinesis. Part of Golgi transport complex. Is expressed in several structures, including adult head; embryonic proventriculus; gland; and spermatozoon. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human COG3 (component of oligomeric golgi complex 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (3453697..3457064, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (3453697..3457064, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in Golgi organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intra-Golgi vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in male meiosis cytokinesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Golgi transport complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Golgi transport complex	IDA Inferred from Direct Assay more info	PubMed
part_of Golgi transport complex	ISS Inferred from Sequence or Structural Similarity more info
located_in cis-Golgi network	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

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