Atg14 Autophagy-related 14 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Atg14provided by FlyBase
Official Full Name: Autophagy-related 14provided by FlyBase
Primary source: FLYBASE:FBgn0039636
Locus tag: Dmel_CG11877
See related: AllianceGenome:FB:FBgn0039636
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: atg14; ATG14; ATG14L; CG11877; Dmel\CG11877
Summary: Predicted to enable phosphatidylinositol 3-kinase regulator activity and protein-membrane adaptor activity. Involved in macroautophagy. Predicted to be part of phosphatidylinositol 3-kinase complex, class III, type I. Predicted to be active in autophagosome. Predicted to be extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Is expressed in organism. Orthologous to human ATG14 (autophagy related 14). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (29116391..29118390)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (24942113..24944112)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables phosphatidylinositol 3-kinase regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-membrane adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in autophagosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in autophagosome membrane docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to starvation	IBA Inferred from Biological aspect of Ancestor more info
involved_in macroautophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitophagy	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in autophagosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extrinsic component of omegasome membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extrinsic component of phagophore assembly site membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of phosphatidylinositol 3-kinase complex, class III	IBA Inferred from Biological aspect of Ancestor more info
part_of phosphatidylinositol 3-kinase complex, class III, type I	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain