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    Pk34A Protein kinase at 34A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34705, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pk34Aprovided by FlyBase
    Official Full Name
    Protein kinase at 34Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028410
    Locus tag
    Dmel_CG5182
    See related
    AllianceGenome:FB:FBgn0028410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5182; Dmel\CG5182; GSK-3a; GSK3a
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Pk34A in Genome Data Viewer
    Location:
    34A7-34A7; 2-47 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13158810..13160173)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13158810..13160173)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44199 Neighboring gene kumgang Neighboring gene DnaJ homolog Neighboring gene Sirtuin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unusual haplotype structure at the proximal breakpoint of In(2L)t in a natural population of Drosophila melanogaster. Andolfatto P, et al. Genetics, 1999 Nov. PMID 10545460, Free PMC Article
    2. Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways. Manola MS, et al. Cells, 2021 Dec 18. PMID 34944088, Free PMC Article
    3. Integrated omics in Drosophila uncover a circadian kinome. Wang C, et al. Nat Commun, 2020 Jun 1. PMID 32483184, Free PMC Article
    4. Genetic variation in food choice behaviour of amino acid-deprived Drosophila. Toshima N, et al. J Insect Physiol, 2014 Oct. PMID 25010547
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein kinase at 34A
    Names
    CG5182-PA
    Pk34A-PA
    NP_609603.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13158810..13160173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135759.2 → NP_609603.1  protein kinase at 34A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609603.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DMW1, Q9U6X0, Q9VK37
      Related
      FBpp0080013
      Conserved Domains (2) summary
      smart00220
      Location:45 → 328
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14137
      Location:39 → 334
      STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KKI9 Q7KKI9
    Q9VK37 Q9VK37

    Gene LinkOut

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