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    soti scotti [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sotiprovided by FlyBase
    Official Full Name
    scottiprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038225
    Locus tag
    Dmel_CG8489
    See related
    AllianceGenome:FB:FBgn0038225
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8489; Dmel\CG8489; Soti
    Summary
    Involved in sperm individualization. Is expressed in elongation stage spermatid and primary spermatocyte. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See soti in Genome Data Viewer
    Location:
    88B7-88B7; 3-55 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14380663..14381699, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10206385..10207421, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene NK7.1 Neighboring gene Dynein axonemal assembly factor 5 Neighboring gene long non-coding RNA:CR44943 Neighboring gene mir-2281 stem loop Neighboring gene crossveinless c Neighboring gene antisense RNA:CR44176 Neighboring gene natalisin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The 3'UTR of the Drosophila CPEB translation factor gene orb2 plays a crucial role in spermatogenesis. Gilmutdinov R, et al. Development, 2021 Sep 1. PMID 34473243, Free PMC Article
    2. Gradients of a ubiquitin E3 ligase inhibitor and a caspase inhibitor determine differentiation or death in spermatids. Kaplan Y, et al. Dev Cell, 2010 Jul 20. PMID 20643358
    3. A Krebs Cycle Component Limits Caspase Activation Rate through Mitochondrial Surface Restriction of CRL Activation. Aram L, et al. Dev Cell, 2016 Apr 4. PMID 27052834
    4. Characterization of Reproductive Dormancy in Male Drosophila melanogaster. Kubrak OI, et al. Front Physiol, 2016. PMID 27932997, Free PMC Article
    5. Eukaryotic translation initiation factor eIF4E-5 is required for spermiogenesis in Drosophila melanogaster. Shao L, et al. Development, 2023 Feb 15. PMID 36695474

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in sperm individualization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sperm individualization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    scotti
    Names
    CG8489-PA
    soti-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14380663..14381699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142101.3 → NP_650358.1  scotti [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650358.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VFK3
      UniProtKB/TrEMBL
      A0A1B2AIW4
      Related
      FBpp0082399
      Conserved Domains (1) summary
      pfam17079
      Location:43 → 147
      SOTI; Male-specific protein scotti
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFK3.1 Q9VFK3

    Gene LinkOut

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