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    CG7768 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39573, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7768provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036415
    Locus tag
    Dmel_CG7768
    See related
    AllianceGenome:FB:FBgn0036415
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7768
    Summary
    Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be active in mitochondrion and nucleus. Orthologous to human PPIF (peptidylprolyl isomerase F). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7768 in Genome Data Viewer
    Location:
    70D4-70D4; 3-42 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (14218204..14218974)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (14211304..14212074)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene nanchung Neighboring gene nuclear fallout Neighboring gene saturn Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quality of regulatory elements in Drosophila retrogenes. Bai Y, et al. Genomics, 2009 Jan. PMID 18848618, Free PMC Article
    2. Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics - An AI-Enabled Biological Target Discovery Platform. Pun FW, et al. Front Aging Neurosci, 2022. PMID 35837482, Free PMC Article
    3. Retroposed new genes out of the X in Drosophila. Betrán E, et al. Genome Res, 2002 Dec. PMID 12466289, Free PMC Article
    4. Conserved properties of Drosophila and human spermatozoal mRNA repertoires. Fischer BE, et al. Proc Biol Sci, 2012 Jul 7. PMID 22378807, Free PMC Article
    5. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cyclosporin A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7768-PA
    CG7768-PB
    NP_648697.1
    NP_729966.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      14218204..14218974
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168584.4 → NP_729966.1  uncharacterized protein Dmel_CG7768, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729966.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5U0U2, Q7K2I4
      Related
      FBpp0075479
      Conserved Domains (1) summary
      cd01926
      Location:4 → 162
      cyclophilin_ABH_like; cyclophilin_ABH_like: Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which ...

    2. NM_140440.3 → NP_648697.1  uncharacterized protein Dmel_CG7768, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648697.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5U0U2, Q7K2I4
      Related
      FBpp0075478
      Conserved Domains (1) summary
      cd01926
      Location:4 → 162
      cyclophilin_ABH_like; cyclophilin_ABH_like: Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K2I4 Q7K2I4

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