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    ssp sunspot [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39375, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sspprovided by FlyBase
    Official Full Name
    sunspotprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036248
    Locus tag
    Dmel_CG17153
    See related
    AllianceGenome:FB:FBgn0036248
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17153; Dmel\CG17153; Ssp
    Summary
    Enables beta-catenin binding activity. Involved in positive regulation of DNA endoreduplication; positive regulation of DNA-templated transcription; and positive regulation of imaginal disc growth. Located in nuclear body and nuclear envelope. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ssp in Genome Data Viewer
    Location:
    68F4-68F4; 3-38 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12118257..12119789)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12111357..12112889)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene versatile Neighboring gene uncharacterized protein Neighboring gene ypsilon schachtel

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The BED finger, a novel DNA-binding domain in chromatin-boundary-element-binding proteins and transposases. Aravind L. Trends Biochem Sci, 2000 Sep. PMID 10973053
    2. Sunspot, a link between Wingless signaling and endoreplication in Drosophila. Taniue K, et al. Development, 2010 May. PMID 20430750
    3. Drak/STK17A Drives Neoplastic Glial Proliferation through Modulation of MRLC Signaling. Chen AS, et al. Cancer Res, 2019 Mar 15. PMID 30530503, Free PMC Article
    4. A network model of the molecular organization of chromatin in Drosophila. van Bemmel JG, et al. Mol Cell, 2013 Feb 21. PMID 23438860
    5. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables beta-catenin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of DNA endoreduplication IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of imaginal disc growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sunspot
    Names
    CG17153-PA
    ssp-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12118257..12119789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140289.3 → NP_648546.1  sunspot [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648546.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTT3
      Related
      FBpp0075724
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 198
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTT3 Q9VTT3

    Gene LinkOut

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