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    pasi2 pasiflora 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41113, updated on 17-Dec-2024

    Summary

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    Official Symbol
    pasi2provided by FlyBase
    Official Full Name
    pasiflora 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0037680
    Locus tag
    Dmel_CG8121
    See related
    AllianceGenome:FB:FBgn0037680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8121; dmCG8121; Dmel\CG8121
    Summary
    Involved in establishment of glial blood-brain barrier; regulation of tube length, open tracheal system; and septate junction assembly. Located in plasma membrane. Is expressed in several structures, including PNS glial cell; adult head; embryonic/larval salivary gland; epithelium; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See pasi2 in Genome Data Viewer
    Location:
    85D11-85D11; 3-48 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9335170..9337459)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5160892..5163181)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Another Drosophila Unc-51-like kinase Neighboring gene long non-coding RNA:CR43301 Neighboring gene doctor no Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fire exit is a potential four transmembrane protein expressed in developing Drosophila glia. With S, et al. Genesis, 2003 Mar. PMID 12640618
    2. microRNA-independent recruitment of Argonaute 1 to nanos mRNA through the Smaug RNA-binding protein. Pinder BD, et al. EMBO Rep, 2013 Jan. PMID 23184089, Free PMC Article
    3. Pasiflora proteins are novel core components of the septate junction. Deligiannaki M, et al. Development, 2015 Sep 1. PMID 26329602, Free PMC Article
    4. The Drosophila septate junctions beyond barrier function: Review of the literature, prediction of human orthologs of the SJ-related proteins and identification of protein domain families. Rouka E, et al. Acta Physiol (Oxf), 2021 Jan. PMID 32603029
    5. Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Hong X, et al. Proc Natl Acad Sci U S A, 2009 Sep 1. PMID 19706460, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in establishment of glial blood-brain barrier IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in establishment of glial blood-brain barrier IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of tube length, open tracheal system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of tube length, open tracheal system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in septate junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in septate junction assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pasiflora 2
    Names
    CG8121-PA
    CG8121-PB
    CG8121-PC
    Pasiflora2
    pasi2-PA
    pasi2-PB
    pasi2-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9335170..9337459
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141626.2 → NP_649883.1  pasiflora 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649883.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHF5
      Related
      FBpp0081495

    2. NM_169267.2 → NP_731334.1  pasiflora 2, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731334.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHF5
      Related
      FBpp0081496

    3. NM_169266.2 → NP_731333.1  pasiflora 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731333.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHF5
      Related
      FBpp0081497
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHF5 Q9VHF5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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