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    Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 [ Mus musculus (house mouse) ]

    Gene ID: 78752, updated on 9-Dec-2024

    Summary

    Official Symbol
    Csgalnact2provided by MGI
    Official Full Name
    chondroitin sulfate N-acetylgalactosaminyltransferase 2provided by MGI
    Primary source
    MGI:MGI:1926002
    See related
    Ensembl:ENSMUSG00000042042 AllianceGenome:MGI:1926002
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Galnact2; 4632415D10Rik
    Summary
    Enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Involved in chondroitin sulfate biosynthetic process. Acts upstream of or within chondroitin sulfate proteoglycan biosynthetic process. Is active in Golgi apparatus. Is expressed in brain; cartilage; knee; and limb long bone. Orthologous to human CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 6.5), lung adult (RPKM 4.1) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Csgalnact2 in Genome Data Viewer
    Location:
    6 F1; 6 55.86 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (118084413..118116132, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (118107452..118139140, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38884 Neighboring gene Lasp1 pseudogene Neighboring gene RasGEF domain family, member 1A Neighboring gene STARR-seq mESC enhancer starr_17132 Neighboring gene STARR-seq mESC enhancer starr_17134 Neighboring gene microRNA 7044 Neighboring gene predicted gene, 23908 Neighboring gene STARR-positive B cell enhancer ABC_E6475 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:118117270-118117379 Neighboring gene STARR-positive B cell enhancer ABC_E2800 Neighboring gene ret proto-oncogene Neighboring gene STARR-seq mESC enhancer starr_17135 Neighboring gene RIKEN cDNA 1700069P05 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 
    • Targeted (4)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    chondroitin sulfate N-acetylgalactosaminyltransferase 2
    Names
    beta4GalNAcT-2
    chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2
    chondroitin sulfate GalNAcT-2
    galNAcT-2
    NP_001349078.1
    NP_084441.3
    XP_006506840.1
    XP_036008295.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362149.1NP_001349078.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC135861
      Consensus CDS
      CCDS20469.1
      UniProtKB/Swiss-Prot
      Q6PAP6, Q8C1F4, Q8R5A2, Q9D2M1
      Conserved Domains (1) summary
      cl11394
      Location:75516
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    2. NM_030165.3NP_084441.3  chondroitin sulfate N-acetylgalactosaminyltransferase 2

      See identical proteins and their annotated locations for NP_084441.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK019496, AK028045, BC060169
      Consensus CDS
      CCDS20469.1
      UniProtKB/Swiss-Prot
      Q6PAP6, Q8C1F4, Q8R5A2, Q9D2M1
      Related
      ENSMUSP00000039819.9, ENSMUST00000049344.15
      Conserved Domains (1) summary
      cl11394
      Location:75516
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      118084413..118116132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152402.1XP_036008295.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X2

      Conserved Domains (1) summary
      cl11394
      Location:67482
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    2. XM_006506777.5XP_006506840.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X1

      See identical proteins and their annotated locations for XP_006506840.1

      UniProtKB/Swiss-Prot
      Q6PAP6, Q8C1F4, Q8R5A2, Q9D2M1
      Conserved Domains (1) summary
      cl11394
      Location:75516
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold