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    azoR3 FMN-dependent NADH-azoreductase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 882554, updated on 11-Sep-2024

    Summary

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    Gene symbol
    azoR3
    Gene description
    FMN-dependent NADH-azoreductase
    Locus tag
    PA3223
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3611254..3611895, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene molecular chaperone CsaA Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transcriptional regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel mechanism for azoreduction. Ryan A, et al. J Mol Biol, 2010 Jul 2. PMID 20417637
    2. Identification of NAD(P)H quinone oxidoreductase activity in azoreductases from P. aeruginosa: azoreductases and NAD(P)H quinone oxidoreductases belong to the same FMN-dependent superfamily of enzymes. Ryan A, et al. PLoS One, 2014. PMID 24915188, Free PMC Article
    3. Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases. Ryan A, et al. Protein Cell, 2010 Aug. PMID 21203919, Free PMC Article
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. detailed enzymic characterization and quinone oxidorductase activity of azoR3 from Pseudomonas aeruginosa
      Title: Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables azobenzene reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FMN-dependent NADH-azoreductase
    NP_251913.1
    • Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3611254..3611895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251913.1 FMN-dependent NADH-azoreductase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251913.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3M5EPP4
      Conserved Domains (1) summary
      COG1182
      Location:1 → 198
      AzoR; FMN-dependent NADH-azoreductase [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HZ17.1

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