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    folX D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 877686, updated on 11-Sep-2024

    Summary

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    Gene symbol
    folX
    Gene description
    D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
    Locus tag
    PA3439
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3846337..3846708)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene short-chain dehydrogenase Neighboring gene GTP cyclohydrolase I Neighboring gene hypothetical protein Neighboring gene type III effector protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FolX and FolM are essential for tetrahydromonapterin synthesis in Escherichia coli and Pseudomonas aeruginosa. Pribat A, et al. J Bacteriol, 2010 Jan. PMID 19897652, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data establish that tetrahydromonapterin formation requires both FolX and FolM, that tetrahydromonapterin is the physiological cofactor for PhhA.
      Title: FolX and FolM are essential for tetrahydromonapterin synthesis in Escherichia coli and Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within tetrahydrobiopterin biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
    NP_252129.1
    • Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3846337..3846708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252129.1 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252129.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2R3J1Z0
      Conserved Domains (1) summary
      PRK11245
      Location:4 → 123
      folX; dihydroneopterin triphosphate 2'-epimerase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HYG7.1

    Gene LinkOut

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