U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cueR protein CueR [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881842, updated on 24-Aug-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    cueR
    Gene description
    protein CueR
    Locus tag
    PA4778
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_002516.2 (5366257..5366655)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene two-component regulator system response regulator PmrA Neighboring gene two-component regulator system signal sensor kinase PmrB Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa. Novoa-Aponte L, et al. J Biol Chem, 2019 Mar 29. PMID 30718281, Free PMC Article
    2. Structural characterizations of metal ion binding transcriptional regulator CueR from opportunistic pathogen pseudomonas aeruginosa to identify its possible involvements in virulence. Bagchi A. Appl Biochem Biotechnol, 2015 Jan. PMID 25342258
    3. Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa. Thaden JT, et al. J Bacteriol, 2010 May. PMID 20233934, Free PMC Article
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa.
      Title: The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa.
    2. The expression of PA3523 is regulated by the dimeric transcription factor CueR having helix-turn-helix DNA binding motif.
      Title: Structural characterizations of metal ion binding transcriptional regulator CueR from opportunistic pathogen pseudomonas aeruginosa to identify its possible involvements in virulence.
    3. Work identifies a cellular function for PA4778 and four other previously unannotated genes (PA3515, PA3516, PA3517, and PA3518) and suggests a potential role for copper in the quorum response. Study propose to name PA4778 cueR.
      Title: Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein CueR
    NP_253466.1
    • Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5366257..5366655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253466.1 protein CueR [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253466.1

      Status: PROVISIONAL

      Conserved Domains (1) summary
      cd01108
      Location:1 → 127
      HTH_CueR; Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HV30.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials