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    PA5437 transcriptional regulator [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 877878, updated on 10-Oct-2024

    Summary

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    Gene symbol
    PA5437
    Gene description
    transcriptional regulator
    Locus tag
    PA5437
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (6119961..6120896)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene pyruvate carboxylase subunit B Neighboring gene acetyl-CoA carboxylase subunit alpha Neighboring gene hypothetical protein Neighboring gene transcriptional regulator Neighboring gene glucose-6-phosphate 1-dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional genomics of PycR, a LysR family transcriptional regulator essential for maintenance of Pseudomonas aeruginosa in the rat lung. Kukavica-Ibrulj I, et al. Microbiology (Reading), 2008 Jul. PMID 18599838
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PycR inactivation results in 100,000-fold attenuation of virulence in the rat lung in vivo.
      Title: Functional genomics of PycR, a LysR family transcriptional regulator essential for maintenance of Pseudomonas aeruginosa in the rat lung.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    transcriptional regulator
    NP_254124.1
    • 'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      6119961..6120896
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_254124.1 transcriptional regulator [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_254124.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A080VKS2
      Conserved Domains (2) summary
      cd08419
      Location:94 → 290
      PBP2_CbbR_RubisCO_like; The C-terminal substrate binding of LysR-type transcriptional regulator (CbbR) of RubisCO operon, which is involved in the carbon dioxide fixation, contains the type 2 periplasmic binding fold
      pfam00126
      Location:5 → 64
      HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family
    Nucleotide Protein
    Heading Accession and Version

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