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    alphaTub85E alpha-Tubulin at 85E [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41183, updated on 9-Dec-2024

    Summary

    Official Symbol
    alphaTub85Eprovided by FlyBase
    Official Full Name
    alpha-Tubulin at 85Eprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003886
    Locus tag
    Dmel_CG9476
    See related
    AllianceGenome:FB:FBgn0003886
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    2t; 85E; a2t; ALPHA 85E; alpha-tub; alpha-Tub; alpha-Tub85E; alpha-tubulin; alpha2; alpha2t; alpha85E; alpha85E-tub; alphaTub; alphaTub2; alphaTub84E; alphatub85E; aTub85E; CG9476; Dmel\CG9476; DTA3; T; Tub; Tub1D; TUBA85E
    Summary
    A structural constituent of cytoskeleton. Involved in unidimensional cell growth. Located in cytoplasmic microtubule and spindle microtubule. Is expressed in several structures, including adult head; embryonic hindgut; imaginal disc; larval muscle cell; and sensory organ cell. Orthologous to human TUBA1B (tubulin alpha 1b) and TUBA1C (tubulin alpha 1c). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See alphaTub85E in Genome Data Viewer
    Location:
    85E6-85E6; 3-49 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9731221..9733250, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5556943..5558972, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene dalmatian Neighboring gene hyperplastic discs Neighboring gene Forkhead box P Neighboring gene sidestep VII Neighboring gene Pinin

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in unidimensional cell growth IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasmic microtubule IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle microtubule IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    alpha-Tubulin at 85E
    Names
    CG9476-PA
    alpha tubulin
    alpha-Tubulin
    alpha-Tubulin 85E
    alpha2-tubulin
    alpha2tubulin
    alpha85E-tubulin
    alphaT
    alphaTub85E-PA
    alphatubulin
    tubulin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9731221..9733250 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079573.5NP_524297.1  alpha-Tubulin at 85E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524297.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B5RJ60, P06604, Q8MYS4, Q9VH86
      UniProtKB/TrEMBL
      K7WKV5, K7XI11
      Related
      FBpp0081565
      Conserved Domains (1) summary
      PTZ00335
      Location:1448
      PTZ00335; tubulin alpha chain; Provisional