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    sinu sinuous [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 46187, updated on 17-Dec-2024

    Summary

    Official Symbol
    sinuprovided by FlyBase
    Official Full Name
    sinuousprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010894
    Locus tag
    Dmel_CG10624
    See related
    AllianceGenome:FB:FBgn0010894
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6524; CG10624; Dmel\CG10624; i8; l(3)06524; Sinu
    Summary
    Involved in several processes, including cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; and septate junction assembly. Located in plasma membrane and septate junction. Is expressed in several structures, including adult head; dorsal epidermis primordium; embryonic dorsal epidermis; embryonic head epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See sinu in Genome Data Viewer
    Location:
    64D3-64D3; 3-14 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5559470..5561598, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5552570..5554698, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene farmer Neighboring gene Succinyl-coenzyme A synthetase beta subunit, GDP-forming Neighboring gene severas

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    sinuous
    Names
    CG10624-PA
    sinu-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      5559470..5561598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139714.4NP_647971.3  sinuous [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647971.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6TDU6, Q8T047, Q9VRM3
      Conserved Domains (1) summary
      pfam13903
      Location:44223
      Claudin_2; PMP-22/EMP/MP20/Claudin tight junction