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    Evi2a ecotropic viral integration site 2a [ Mus musculus (house mouse) ]

    Gene ID: 14017, updated on 9-Dec-2024

    Summary

    Official Symbol
    Evi2aprovided by MGI
    Official Full Name
    ecotropic viral integration site 2aprovided by MGI
    Primary source
    MGI:MGI:95458
    See related
    Ensembl:ENSMUSG00000078771 AllianceGenome:MGI:95458
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Evi2; Evi-2
    Summary
    Predicted to be located in membrane. Is expressed in several structures, including central nervous system; heart; hemolymphoid system; and ureter. Orthologous to human EVI2A (ecotropic viral integration site 2A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 10.5), spleen adult (RPKM 8.6) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Evi2a in Genome Data Viewer
    Location:
    11 B5; 11 46.81 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (79417386..79421435, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (79526560..79530609, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene neurofibromin 1 Neighboring gene STARR-positive B cell enhancer ABC_E8431 Neighboring gene STARR-positive B cell enhancer ABC_E7024 Neighboring gene STARR-positive B cell enhancer ABC_E5254 Neighboring gene STARR-positive B cell enhancer ABC_E11485 Neighboring gene oligodendrocyte myelin glycoprotein Neighboring gene ecotropic viral integration site 2b Neighboring gene ecotropic viral integration site 2 Neighboring gene STARR-positive B cell enhancer ABC_E11768 Neighboring gene RAB11 family interacting protein 4 (class II) Neighboring gene RAB11 family interacting protein 4 (class II), opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:79428461-79428644 Neighboring gene predicted gene, 23293

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Readthrough Evi2

    Readthrough gene: Evi2, Included gene: Evi2b

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein EVI2A
    Names
    EVI-2A
    ecotropic viral integration site 2A protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033711.1NP_001028883.1  protein EVI2A precursor

      See identical proteins and their annotated locations for NP_001028883.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL591174, BC038124
      Consensus CDS
      CCDS25122.1
      UniProtKB/Swiss-Prot
      P20934, Q6DKP1
      UniProtKB/TrEMBL
      Q3TBB7
      Related
      ENSMUSP00000159581.1, ENSMUST00000133148.3
      Conserved Domains (1) summary
      pfam05399
      Location:1223
      EVI2A; Ectropic viral integration site 2A protein (EVI2A)
    2. NM_010161.3NP_034291.1  protein EVI2A precursor

      See identical proteins and their annotated locations for NP_034291.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL591174, BC038124
      Consensus CDS
      CCDS25122.1
      UniProtKB/Swiss-Prot
      P20934, Q6DKP1
      UniProtKB/TrEMBL
      Q3TBB7
      Related
      ENSMUSP00000099526.4, ENSMUST00000103236.4
      Conserved Domains (1) summary
      pfam05399
      Location:1223
      EVI2A; Ectropic viral integration site 2A protein (EVI2A)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      79417386..79421435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)