Abcf3 ATP-binding cassette, sub-family F member 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Abcf3provided by MGI
Official Full Name: ATP-binding cassette, sub-family F member 3provided by MGI
Primary source: MGI:MGI:1351656
See related: Ensembl:ENSMUSG00000003234 AllianceGenome:MGI:1351656
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable ATP binding activity. Predicted to be involved in defense response to virus. Is expressed in head mesenchyme; limb; skeletal musculature; tail; and tongue mesenchyme. Orthologous to human ABCF3 (ATP binding cassette subfamily F member 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in testis adult (RPKM 21.7), cerebellum adult (RPKM 14.5) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 16 A3; 16 12.46 cM

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (20367309..20380357)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (20548556..20561603)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

characterization of ABCF3 protein and its interaction with OAS1B
Title: Biochemical characterization of the mouse ABCF3 protein, a partner of the flavivirus-resistance protein OAS1B.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI326318 (e-PCR)
- UniSTS:160546

NoName (e-PCR)
- UniSTS:237468

MARC_12819-12820:999872670:3 (e-PCR)
- UniSTS:267453

BB119416 (e-PCR)
- UniSTS:186067

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATP binding	IBA Inferred from Biological aspect of Ancestor more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in defense response to virus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATP-binding cassette sub-family F member 3

Names: ATP-binding cassette, sub-family F (GCN20), member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_013852.2 → NP_038880.1 ATP-binding cassette sub-family F member 3

See identical proteins and their annotated locations for NP_038880.1

Status: VALIDATED

Source sequence(s)

AC087898, BC032923, CD540120

Consensus CDS

CCDS28049.1

UniProtKB/Swiss-Prot

Q8K268, Q9JL49

UniProtKB/TrEMBL

A0A338P6L5

Related

ENSMUSP00000003319.6, ENSMUST00000003319.6

Conserved Domains (4) summary

cd03221
Location:492 → 683

ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F

PLN03073
Location:6 → 700

PLN03073; ABC transporter F family; Provisional

pfam12848
Location:395 → 477

ABC_tran_Xtn; ABC transporter

cl21455
Location:266 → 363

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases