Luzp2 leucine zipper protein 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Luzp2provided by MGI
Official Full Name: leucine zipper protein 2provided by MGI
Primary source: MGI:MGI:1889615
See related: Ensembl:ENSMUSG00000063297 AllianceGenome:MGI:1889615
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D130073E01; 9330154K17Rik
Summary: Predicted to be located in extracellular region. Is expressed in diencephalon lateral wall ventricular layer; midbrain ventricular layer; pons marginal layer; and pons ventricular layer. Orthologous to human LUZP2 (leucine zipper protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in frontal lobe adult (RPKM 21.2), cortex adult (RPKM 13.6) and 4 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 B5; 7 33.23 cM

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (54484936..54918636)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (54835245..55268888)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

mapping of Chrna7 and Luzp2 neuronal transcriptional enhancers in a mouse model of Prader-Willi and Angelman syndromes
Title: Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (1) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

MHAa67a6.seq (e-PCR)
- UniSTS:125259

D7Mit87 (e-PCR), detects polymorphism
- UniSTS:131294

BB274933 (e-PCR)
- UniSTS:208123

AI837749 (e-PCR)
- UniSTS:208124

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: leucine zipper protein 2

Names: leucine zipper motif 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.